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Effect of Fibrates on Lipid Profiles and Cardiovascular Outcomes: A Systematic Review

Abourbih S, Filion KB, Joseph L, et al.
Am J Med.   2009;122(10):962.e1-e8.
  KEYWORDS: CVD , Fibric acid

Long-term effects of intensive glucose lowering on cardiovascular outcomes.

ACCORD Study Group, Gerstein HC, Miller ME, Genuth S, et al for the ACCORD Study Group.
N Engl J Med.   2011;364(9):818-828.
  KEYWORDS: CVD , Diabetes , MI
 
Click for Full Abstract

Effects of intense exercise and moderate caloric restriction on cardiovascular risk factors and inflammation

Ahmadi N, Eshaghian S, Huizenga R, Sosnin K, Ebrahimi R, Siegel R.
Am J Med.  2011;124(10):978-982.
  KEYWORDS: CVD , Diet , Exercise , Obesity/overweight , Risk assessment

Effects of physical activity on cardiovascular disease

Ahmed HM, Blaha MJ, Nasir K, Rivera JJ, Blumenthal RS.
Am J Cardiol.   2011 Oct 17. [Epub ahead of print]
  KEYWORDS: CVD , Exercise
 
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An HMG-CoA Reductase Inhibitor, Cerivastatin, Suppresses Growth of Macrophages Expressing Matrix Metalloproteinases and Tissue Factor In Vivo and In Vitro

Aikawa M, Rabkin E, Sugiyama S, et al.
Circulation.  2001;103:276-283.
  KEYWORDS: HMG-CoA reductase inhibitor , Thrombus
 
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Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy

AIM-HIGH Investigators, Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, et al.
N Engl J Med  2011 Dec 15;365(24):2255-2267.
  KEYWORDS: Atherosclerosis , Combination therapy , CVD , Dyslipidemia , HDL-C , HMG-CoA reductase inhibitor , LDL-C , Nicotinic acid , Triglycerides

SPARCL: Stroke Prevention by Aggressive Reduction in Cholesterol Levels
High-Dose Atorvastatin After Stroke or Transient Ischemic Attack

Amarenco P, Bogousslavsky J, Callahan A III, et al, on behalf of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators.
N Engl J Med.  2006;355:549-559.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , LDL-C

The Pathophysiology of Cigarette Smoking and Cardiovascular Disease: An Update

Ambrose JA, Barua RS.
J Am Coll Cardiol.   2004;43:1731-1737.
  KEYWORDS: Atherosclerosis , CAD , CVD
 
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COURAGE: Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation
Management of the Patient with Chronic Ischemic Heart Disease: Implications of the COURAGE trial.

Amsterdam EA

 

  KEYWORDS: CAD , PCI , Post CABG , Revascularization , Stents

Aliskiren-Based Therapy Lowers Blood Pressure More Effectively Than Ramipril-Based Therapy in Patients With Hypertension: A 6-Month, Randomized, Double-Blind Trial

Anderson K, Weinberger MH, Egan B, et al.

 

  KEYWORDS: Hypertension

Inflammatory/Antiinflammatory Properties of High-Density Lipoprotein Distinguish Patients From Control Subjects Better Than High-Density Lipoprotein Cholesterol Levels and Are Favorably Affected by Simvastatin Treatment

Ansell BJ, Navab M, Hama S, et al.
Circulation.   2003;108:2751-2756.
  KEYWORDS: CHD , HDL-C , HMG-CoA reductase inhibitor , Inflammation
 
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Treatment Blood Pressure Targets for Hypertension

Arguedas JA, Perez MI, Wright JM.
Cochrane Database Syst Rev.  2009;(3):CD004349.
  KEYWORDS: Hypertension

GREACE: GREek Atorvastatin and Coronary-heart-disease Evaluation
 Treatment with Atorvastatin to the National Cholesterol Educational Program Goal Versus "Usual" Care in Secondary Coronary Heart Disease Prevention: The GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) Study

Athyros VG, Papageorgiou AA, Mercouris BR, et al.
Curr Med Res Opin.  2002;18:220-228.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor
 
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Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis

Athyros VG, Tziomalos K, Gossios TD, Griva T, Anagnostis P, Kargiotis K, Pagourelias ED, Theocharidou E, Karagiannis A, Mikhailidis DP; GREACE Study Collaborative Group.
Lancet.  2010;376(9756):1916-1922.
  KEYWORDS: HMG-CoA reductase inhibitor
 
Click for Full Abstract

Cardiovascular Disease Mortality in Familial Forms of Hypertriglyceridemia: A 20-year Prospective Study

Austin MA, McKnight B, Edwards KL, et al.
Circulation.  2000;101:2777-2782.
  KEYWORDS: CVD , Familial hypertriglyceridemia , Triglycerides
 
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Efficacy and Safety of Cholesterol-Lowering Treatment: Prospective Meta-Analysis of Data From 90,056 Participants In 14 Randomised Trials of Statins

Baigent C, Keech A, Kearney PM, et al, for the Cholesterol Treatment Trialists’ (CCT) Collaborators.
Lancet.  2005;366:1267-1278.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

The Metabolic Syndrome Predicts Carotid Intima-Media Thickness No Better Than the Sum of Individual Risk Factors in a Lipid Clinic Population

Baldassarre D, Werba JP, Castelnuovo S, et al.
Atherosclerosis.   2010;210(1):214-219.
  KEYWORDS: Carotid atherosclerosis , CIMT , Metabolic Syndrome
 
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SEACOAST: Safety and Efficacy of A COmbination of niAcin ER and Simvastatin in paTients with Dyslipidemia
Comparison of the Safety and Efficacy of a Combination Tablet of Niacin Extended Release and Simvastatin vs Simvastatin Monotherapy in Patients With Increased Non–HDL Cholesterol (from the SEACOAST I Study).

Ballantyne CM, Davidson MH, McKenny J, et al.
Am J Cardiol.  2008;101(10):1428-1436.
  KEYWORDS: ATP III , Combination therapy , HDL-C , HMG-CoA reductase inhibitor , LDL-C , Nicotinic acid

Effect of Ezetimibe Coadministered With Atorvastatin in 628 Patients With Primary Hypercholesterolemia; A Prospective, Randomized, Double-Blind Trial

Ballantyne CM, Houri J, Notarbartolo A, et al, and for the Ezetimibe Study Group.
Circulation.  2003;107:2409-2415.
  KEYWORDS: Combination therapy , Ezetimibe , HDL-C , HMG-CoA reductase inhibitor , LDL-C , Triglycerides
 
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Angiotensin receptor blockers and risk of myocardial infarction: meta-analyses and trial sequential analyses of 147,020 patients from randomised trials

Bangalore S, Kumar S, Wetterslev J, Messerli FH.
BMJ.   2011;342:d2234. doi: 10.1136/bmj.d2234.
  KEYWORDS: CVD , Hypertension , MI

Heart Disease Risk Factors Predict Erectile Dysfunction 25 Years Later (The Rancho Bernardo Study)

Barrett-Connor E.
Am J Cardiol.  2005;96(suppl 2):3M-7M.
  KEYWORDS: CAD , CVD , Diabetes , Endothelium , Metabolic Syndrome , Obesity/overweight

HDL Cholesterol, Very Low Levels of LDL Cholesterol, and Cardiovascular Events

Barter P, Gotto AM, LaRosa JC, et al, for the Treating to New Targets Investigators.
N Engl J Med.  2007;357(13):1301-1310.
  KEYWORDS: CHD , HDL-C , HMG-CoA reductase inhibitor , LDL-C

Meta-Analysis of Data from the Six Primary Prevention Trials of Cardiovascular Events Using Aspirin

Bartolucci AA, Howard G.
Am J Cardiol.  2006;98:746-750.
  KEYWORDS: Aspirin , CHD , CVD , MI
 
Click for Full Abstract

Meta-analysis of multiple primary prevention trials of cardiovascular events using aspirin.

Bartolucci AA, Tendera M, Howard G.
Am J Cardiol.   2011;107(12):1796-1801.
  KEYWORDS: Aspirin , CVD
 
Click for Full Abstract

Long-Term Benefit of Statin Therapy Initiated During Acute Coronary Syndromes: A Meta-Analysis of Randomized Trials

Bavry AA, Girish RM, Kumbhani DJ, Borek PP, Askari AT, Bhatt DL.

 

  KEYWORDS: HMG-CoA reductase inhibitor , LDL-C

Addition of Colesevelam HCL To Metformin (MET)-Based Therapy in Patients With Inadequately Controlled Type 2 Diabetes Mellitus Improves Glycemic Control

Bay H, Goldberg RB, Truitt K., Dmuchowski C, Jones M.

 

  KEYWORDS: Diabetes

Diabetes and Atherosclerosis–Epidemiology, Pathophysiology, and Management

Beckman JA, Creager, MA, Libby P.
JAMA.  2002;287:2570-2581.
  KEYWORDS: Diabetes


Click for Full Abstract

BIP: Bezafibrate Infarction Prevention
 Secondary Prevention by Raising HDL Cholesterol and Reducing Triglycerides in Patients with Coronary Artery Disease. The Bezafibrate Infarction Prevention (BIP) Study

Behar S, Brunner D, Kaplinsky E, Mandelzweig L, Benderly M for the Bezafibrate Infarction Prevention (BIP) Study Group.
Circulation.  2000;102:21-27.
  KEYWORDS: CHD , Fibric acid , HDL-C , MI , Triglycerides
 
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Endothelial Function: From Vascular Biology to Clinical Applications

Behrendt D, Ganz P.
Am J Cardiol.  2002;90(suppl):40L-48L.
  KEYWORDS: Atherosclerosis , Endothelium , Inflammation
 
Click for Full Abstract

Should Diastolic and Systolic Blood Pressure Be Considered for Cardiovascular Risk Evaluation: A Study in Middle-Aged Men and Women

Benetos A, Thomas F, Safar ME, Bean KE, Guize L.
J Am Coll Cardiol.  2001;37:163-168.
  KEYWORDS: Hypertension
 
Click for Full Abstract

BHS: The Bogalusa Heart Study
 Childhood Risk Factors Predict Adult Risk Associated with Subclinical Cardiovascular Disease: the Bogalusa Heart Study

Berenson GS, for the Bogalusa Heart Study Research Group.
Am J Cardiol.  2002;90(suppl):3L-7L.
  KEYWORDS: CVD , Young adults
 
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Evidence for Identifying Children at Risk for Being Overweight, Cardiovascular Disease, and Type 2 Diabetes in Primary Care

Bindler RM, Bruya MA.
J Pediatr Health Care.  2006;20:82-87.
  KEYWORDS: CVD , Diabetes , MI , Obesity/overweight

Projected Life-Expectancy Gains With Statin Therapy for Individuals With Elevated C-Reactive Protein Levels

Blake GJ, Ridker PM, Kuntz KM.
J Am Coll Cardiol.  2002;40:49-55.
  KEYWORDS: CRP
 
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Effects of Exercise and Stress Management Training on Markers of Cardiovascular Risk in Patients With Ischemic Heart Disease: A Randomized Controlled Trial

Blumenthal JA, Sherwood A, Babyak MA, et al.
JAMA.  2005;293:1626-1634.
  KEYWORDS: CVD

Detecting Occult Coronary Disease in a High-Risk Asymptomatic Population

Blumenthal RS, Becker DM, Yanek LR, et al.
Circulation.  2003;107:702-707.
  KEYWORDS: CAD , Family history
 
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Medical Therapy Versus Coronary Angioplasty in Stable Coronary Artery Disease: A Critical View of the Literature

Blumenthal RS, Cohn G, Schulman SP.
J Am Coll Cardiol.  2000;36:668-673.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor , PCI , Revascularization
 
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Association of Overweight With Increased Risk of Coronary Heart Disease Partly Independent of Blood Pressure and Cholesterol Levels: A Meta-Analysis of 21 Cohort Studies Including More Than 300,000 Persons

Bogers RP, Bemelmans WJE, Hoogenveen RT, et al, for the BMI-CHD Collaboration Investigators.
Arch Intern Med.  2007;167(16):1720-1728.
  KEYWORDS: BMI , CHD , Hypertension , Obesity/overweight

The Role of Cardiovascular Disease in the Identification and Management of Depression by Primary Care Physicians

Bogner HR, Ford DE, Gallo JJ.
Am J Geriatr Psychiatry.  2006;14:71-78.
  KEYWORDS: CVD
 
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Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis.

Bolland MJ, Grey A, Avenell A, Gamble GD, Reid IR.
BMJ.   2011;342:d2040. doi: 10.1136/bmj.d2040.
  KEYWORDS: CVD , Women
 
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Relation Between Age and Cardiovascular Disease in Men and Women With Diabetes Compared With Non-diabetic People: A Population-based Retrospective Cohort Study

Booth GL, Kapral MK, Fung K, Tu JV.
Lancet.   2006;368:29-36.
  KEYWORDS: CHD , CVD , Diabetes , Framingham Heart Study , MI

C-Reactive Protein as a Risk Factor for Coronary Heart Disease: A Systematic Review and Meta-Analyses for the U.S. Preventive Services Task Force

Buckley DI, Fu R, Freeman M, Rogers K, Helfand M.
Ann Intern Med.  2009;151(7):483-495.
  KEYWORDS: CHD , CRP
 
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Independent and Joint Effects of Antibodies to Human Heat-Shock Protein 60 and Chlamydia pneumoniae Infection in the Development of Coronary Atherosclerosis

Burian K, Kis Z, Virok D, et al.
Circulation.  2001;103:1503-1508.
  KEYWORDS: CAD , Infection
 
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Intensive Versus Moderate Lipid Lowering With Statins After Acute Coronary Syndromes

Cannon CP, Braunwald E, McCabe CH, et al, for the Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis in Myocardial Infarction 22 Investigators.
N Engl J Med.   2004;350:1495-1504.
  KEYWORDS: CABG , HMG-CoA reductase inhibitor , LDL-C , PCI

Meta-Analysis of Cardiovascular Outcomes Trials Comparing Intensive Versus Moderate Statin Therapy

Cannon CP, Steinberg BA, Murphy SA, Mega JL, Braunwald E.
J Am Coll Cardiol.  2006;48:438-445.
  KEYWORDS: CHD , CVD , HMG-CoA reductase inhibitor , MI
 
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Postprandial blood glucose predicts cardiovascular events and all-cause mortality in type 2 diabetes in a 14-year follow-up

Cavalot F, Pagliarino A, Valle M, et al.
Diabetes Care.   2011;34(10):2237-2243.
  KEYWORDS: CVD , Diabetes , Risk assessment

Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited

Ceriello A, Motz E.
Arterioscler Thromb Vasc Biol.  2004;24:1-8.
  KEYWORDS: CVD , Diabetes , Diet , Endothelium , HMG-CoA reductase inhibitor , Insulin resistance

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Dietary Recommendations in the Prevention and Treatment of Coronary Heart Disease: Do We Have the Ideal Diet Yet?

Chahoud G, Aude YW, Mehta JL.
Am J Cardiol.   2004;94:1260-1267.
  KEYWORDS: CHD , CVD , Diet

Non-Diabetic Hyperglycaemia and Cardiovascular Risk: Moving Beyond Categorisation to Individual Interpretation of Absolute Risk

Chamnan P, Simmons RK, Jackson R, et al.
Diabetologia.  2010. Epub ahead of print.
 

Early and Sustained Survival Benefit Associated With Statin Therapy at the Time of Percutaneous Coronary Intervention

Chan AW, Bhatt DL, Chew DP, et al.
Circulation.  2002;105:691-696.
  KEYWORDS: HMG-CoA reductase inhibitor , PCI
 
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Relation of Inflammation and Benefit of Statins After Percutaneous Coronary Interventions

Chan AW, Bhatt DL, Chew DP, et al.
Circulation.  2003;107:1750-1756.
  KEYWORDS: CAD , CRP , HMG-CoA reductase inhibitor , Inflammation , MI , PCI
 
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Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women

Chan KA, Andrade SE, Boles M, et al.
Lancet.  2000;355:2185-2188.
  KEYWORDS: Fracture , HMG-CoA reductase inhibitor , Women
 
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Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

Chapman MJ, Ginsberg HN, Amarenco P, Andreotti F, Borén J, Catapano AL, Descamps OS, Fisher E, Kovanen PT, Kuivenhoven JA, Lesnik P, Masana L, Nordestgaard BG, Ray KK, Reiner Z, Taskinen MR, Tokgözoglu L, Tybjærg-Hansen A, Watts GF; European Atherosclerosis Society Consensus Panel.
Eur Heart J.   2011;32(11):1345-1361.
  KEYWORDS: Carotid atherosclerosis , CHD , CIMT , Risk assessment
 
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The Metabolic Syndrome and Chronic Kidney Disease in U.S. Adults

Chen J, Muntner P, Hamm LL, et al.
Ann Intern Med.   2004;140:167-174.
  KEYWORDS: BMI , HDL-C , Hypertension , Metabolic Syndrome , MI
 
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Addition of Clopidogrel to Aspirin in 45,852 Patients With Acute Myocardial Infarction: Randomised Placebo-Controlled Trial

Chen ZM, Jiang LX, Chen YP, et al, for the COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group
Lancet.  2005;366:1607-1621.
  KEYWORDS: Aspirin , Combination therapy , MI
 
Click for Full Abstract

A Meta-Analysis Comparing the Effect of Thiazolidinediones on Cardiovascular Risk Factors

Chiquette E, Ramirez G, DeFronzo R.
Arch Intern Med.  2004;164:2097-2104.
  KEYWORDS: CVD , Diabetes
 
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Healthy Lifestyle Factors in the Primary Prevention of Coronary Heart Disease Among Men: Benefits Among Users and Nonusers of Lipid-lowering and Antihypertensive Medications

Chiuve SE, McCullough ML, Sacks FM, Rimm EB.
Circulation.   2006;114:160-167.
  KEYWORDS: CHD , Diet , Hypertension
 
Click for Full Abstract

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 Report

Chobanian AV, Bakris GL, Black HR, et al, and the National High Blood Pressure Education Program Coordinating Committee.
JAMA.  2003;289:2560-2572.
  KEYWORDS: Hypertension

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

Cholesterol Treatment Trialists’ (CTT) Collaboration.
Lancet.   2010;376(9753):1670-1681.
  KEYWORDS: HMG-CoA reductase inhibitor

Metabolic Syndrome and Diabetes, Alone and in Combination, As Predictors of Cardiovascular Disease Mortality Among Men

Church TS, Thompson AM, Katzmarzyk PT, et al.
Circulation.  2009;32(7):1289-1294.
  KEYWORDS: CVD , Diabetes , Metabolic Syndrome

Raising High-Density Lipoprotein in Humans Through Inhibition of Cholesteryl Ester Transfer Protein: An Initial Multidose Study of Torcetrapib

Clark RW, Sutfin TA, Ruggeri RB.
Arterioscler Thromb Vasc Biol.   2004;24:490-497.
  KEYWORDS: Atherosclerosis , HDL-C
 
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Benefits of Lipid Lowering on Vascular Reactivity in Patients with Coronary Artery Disease and Average Cholesterol Levels: A Mechanism for Reducing Clinical Events?

Cohen JD, Drury JH, Ostdiek J, et al.
Am Heart J.  2000;139(4):734-738.
  KEYWORDS: CAD , Endothelium , LDL-C
 
Click for Full Abstract

CARDS: Collaborative Atorvastatin Diabetes Study
Primary Prevention of Cardiovascular Disease With Atorvastatin in Type 2 Diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): Multicentre Randomised Placebo-Controlled Trial

Colhoun HM, Betteridge DJ, Durrington PN, et al, on behalf of the CARDS investigators.
Lancet.  2004;364:685-696.
  KEYWORDS: CVD , Diabetes , HMG-CoA reductase inhibitor
 
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HPS: Heart Protection Study
 MRC/BHF Heart Protection Study of Antioxidant Vitamin Supplementation in 20,536 High-Risk Individuals: A Randomised Placebo-Controlled Trial

Collins R, Armitage J, Parish S, Sleight P, Peto R, writing for the Heart Protection Study Collaborative Group.
Lancet.  2002;360:23-33.
  KEYWORDS: CVD , Diet , LDL-C , Older adults
 
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HPS: Heart Protection Study
 MRC/BHF Heart Protection Study of Cholesterol Lowering With Simvastatin in 20,536 High-Risk Individuals: A Randomised Placebo-Controlled Trial

Collins R, Armitage J, Parish S, Sleight P, Peto R, writing for the Heart Protection Study Collaborative Group.
Lancet.  2002;360:7-22.
  KEYWORDS: CVD , Diabetes , HMG-CoA reductase inhibitor , LDL-C , Older adults
 
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HPS: Heart Protection Study
 MRC/BHF Heart Protection Study of Cholesterol-lowering With Simvastatin in 5,963 People With Diabetes: A Randomised Placebo-controlled Trial

Collins R, Armitage J, Parish S, Sleight P, Peto R, writing for the Heart Protection Study Collaborative Group.
Lancet.  2003;361:2005-2016.
  KEYWORDS: CVD , Diet , LDL-C , Older adults
 
Click for Full Abstract

ACTIVE W: Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events
 Clopidogrel Plus Aspirin Versus Oral Anticoagulation for Atrial Fibrillation in the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE W): A Randomised Controlled Trial

Connolly S, Pogue J, Hart R, et al, on behalf of the ACTIVE investigators.
Lancet.   2006;367:1903-1912.
  KEYWORDS: Aspirin , Combination therapy

HDL Cholesterol Protects Against Cardiovascular Disease in Both Genders, At All Ages and At All Levels of Risk

Cooney MT, Dudina A, De Bacquer D, et al.
Atherosclerosis.  2009;206(2):611-616.
  KEYWORDS: CVD , HDL-C
 
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Prognostic Value of Pharmacological Stress Echocardiography in Diabetic and Nondiabetic Patients With Known or Suspected Coronary Artery Disease

Cortigiani L, Bigi R, Sicari R, Landi P, Bovenzi F, Picano E.
J Am Coll Cardiol.  2006;47:605-610.
  KEYWORDS: CAD , Diabetes

Differential Effects of Lipid-Lowering Therapies on Stroke Prevention: A Meta-analysis of Randomized Trials

Corvol JC, Bouzamondo A, Sirol M, Hulot JS, Sanchez P, Lechat P.
Arch Intern Med.  2003;163:669-676.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor
 
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Central obesity and survival in subjects with coronary artery disease a systematic review of the literature and collaborative analysis with individual subject data

Coutinho T, Goel K, Corrêa de Sá D, et al.
J Am Coll Cardiol.   2011;57(19):1877-1886.
  KEYWORDS: BMI , CAD , Obesity/overweight
 
Click for Full Abstract

METEOR: Measuring Effects on Intima-Media Thickness: an Evaluation of Rosuvastatin Trial
 Effect of Rosuvastatin on Progression of Carotid Intima-Media Thickness in Low-Risk Individuals With Subclinical Atherosclerosis: The METEOR Trial

Crouse JR III, Raichlen JS, Riley WA, et al, for the METEOR Study Group.
JAMA.  2007;297:1344-1353.
  KEYWORDS: Atherosclerosis , Carotid atherosclerosis , CIMT , HDL-C , HMG-CoA reductase inhibitor , LDL-C

Effects of Increasing High-Density Lipoprotein Cholesterol and Decreasing Low-Density Lipoprotein Cholesterol on the Incidence of First Acute Coronary Events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study)

Cui Y, Watson DJ, Girman CJ, et al.
Am J Cardiol.   2009;104(6):829-834.
  KEYWORDS: Diet , HDL-C , HMG-CoA reductase inhibitor , LDL-C

Impact of the Metabolic Syndrome on Macrovascular and Microvascular Outcomes in Type 2 Diabetes Mellitus: United Kingdom Prospective Diabetes Study 78

Cull CA, Jensen CC, Retnakaran R, Holman RR.
Circulation.  2007;116(19):2119-2126.
  KEYWORDS: ATP III , CVD , Diabetes , Metabolic Syndrome

Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative

Culver AL, Ockene IS, Balasubramanian R, Olendzki BC, Sepavich DM, Wactawski-Wende J, et al.
Arch Intern Med  2012;172(2):144-152.
  KEYWORDS: Diabetes , HMG-CoA reductase inhibitor , Women

Global and Regional Mortality from Ischaemic Heart Disease and Stroke Attributable to Higher-Than-Optimum Blood Glucose Concentration: Comparative Risk Assessment

Danaei G, Lawes CMM, Hoorn SV, Murray CJL, Ezzati M.
Lancet.  2006;368:1651-1659.
  KEYWORDS: Diabetes

Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction: A Randomized Trial

Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ.
JAMA.  2005;293:43-53.
  KEYWORDS: CHD , CVD , Diet

Effects of Prescription Omega-3-Acid Ethyl Esters on Lipoprotein Particle Concentrations, Apolipoproteins AI and CIII, and Lipoprotein-Associated Phospholipase A2 Mass in Statin-Treated Subjects With Hypertriglyceridemia

Davidson MH, Maki KC, Bays H, Carter R, Ballantyne CM.
J Clin Lipidol.   2009;3(5):332-340.
  KEYWORDS: Omega-3 polyunsaturated fatty acids

Effects of Consumption of Pomegranate Juice on Carotid Intima-Media Thickness in Men and Women at Moderate Risk for Coronary Heart Disease

Davidson MH, Maki KC, Dicklin MR, et al.
Am J Cardiol.  2009;104(7):936-942.
  KEYWORDS: CHD , CIMT
 
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Ezetimibe Coadministered With Simvastatin in Patients With Primary Hypercholesterolem

Davidson MH, McGarry T, Bettis R, et al, on behalf of the Ezetimibe Study Group.
J Am Coll Cardiol.  2002;40:2125-2134i.
  KEYWORDS: Combination therapy , HDL-C , HMG-CoA reductase inhibitor , LDL-C
 
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Effect of a Combined Therapeutic Approach of Intensive Lipid Management, Omega-3 Fatty Acid Supplementation, and Increased serum 25 (OH) Vitamin D on Coronary Calcium Scores in Asymptomatic Adults

Davis W, Rockaway S, Kwasny M.
Am J Ther.  2009;16(4):326-32.
  KEYWORDS: Omega-3 polyunsaturated fatty acids
 
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Prevalence of the Metabolic Syndrome in American Adolescents: Findings From the Third National Health and Nutrition Examination Survey

de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai N.
Circulation.  2004;110:2494-2497.
  KEYWORDS: ATP III , Metabolic Syndrome , Young adults

Efficacy and Safety of Statin Therapy in Children With Familial Hypercholesterolemia: A Randomized, Double-Blind, Placebo-Controlled Trial With Simvastatin

de Jongh S, Ose L, Szamosi T, et al, for the Simvastatin in Children Study Group.
Circulation.  2002;106:2231-2237.
  KEYWORDS: Family history , HMG-CoA reductase inhibitor , LDL-C
 
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A to Z: Aggrastat to Zocor Trial
 Early Intensive vs a Delayed Conservative Simvastatin Strategy in Patients With Acute Coronary Syndromes: Phase Z of the A to Z Trial

de Lemos JA, Blazing MA, Wiviott SD, et al, for the A to Z Investigators.
JAMA.  2004;292:1307-1316.
  KEYWORDS: HMG-CoA reductase inhibitor , MI

Lyon Diet Heart Study
 Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction: Final Report of the Lyon Diet Heart Study

de Lorgeril M, Salen P, Martin J-L, Monjaud I, Delaye J, MD, Mamelle N.
Circulation.  1999;99:779-785.
  KEYWORDS: Diet , MI
 
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Reduction of Low-Density Lipoprotein Cholesterol in Patients with Coronary Heart Disease and Metabolic Syndrome: Analysis of the Treating to New Targets Study

Deedwania P, Barter P, Carmena R, et al, for the Treating to New Targets Investigators.
Lancet.  2006;368:919-928.
  KEYWORDS: CHD , CVD , Diabetes , HMG-CoA reductase inhibitor , LDL-C , Metabolic Syndrome , MI

Metabolic Syndrome and 10-Year Cardiovascular Disease Risk in the Hoorn Study

Dekker JM, Girman C, Rhodes T, et al.
Circulation.  2005;112:666-673.
  KEYWORDS: CIMT , CVD , Metabolic Syndrome

Strong Heart Study
 Impact of Diabetes on Cardiac Structure and Function: The Strong Heart Study

Devereux RB, Roman MJ, Paranicas M, et al.
Circulation.  2000;101:2271-2276.
  KEYWORDS: BMI , Diabetes
 
Click for Full Abstract

HMG-CoA Reductase Inhibitors Regulate Inflammatory Transcription Factors in Human Endothelial and Vascular Smooth Muscle Cells

Dichtl W, Dulak J, Frick M, et al.
Arterioscler Thromb Vasc Biol.  2003;23:58-63.
  KEYWORDS: Atherosclerosis , Endothelium , HMG-CoA reductase inhibitor , Inflammation

 
Click for Full Abstract

Serum Lipid Levels and the Risk of Venous Thrombosis

Doggen CJM, Smith NL, Lemaitre RN, Heckbert SR, Rosendaal FR, Psaty BM.
Arterioscler Thromb Vasc Biol.  2004;24:1-6.
  KEYWORDS: HDL-C , Thrombus , Triglycerides , Women
 
Click for Full Abstract

Diabetes and Mortality Following Acute Coronary Syndromes

Donahoe SM, Stewart GC, McCabe CH, et al.
JAMA.  2007;298(7):765-775.
  KEYWORDS: CVD , Diabetes , MI

Relation of Triglyceride Levels, Fasting and Nonfasting, to Fatal and Nonfatal Coronary Heart Disease

Eberly LE, Stamler J, Neaton JD, for the Multiple Risk Factor Intervention Trial Research Group
Arch Intern Med.  2003;163:1077-1083.
  KEYWORDS: CHD , Triglycerides
 
Click for Full Abstract

An Update on Aspirin in the Primary Prevention of Cardiovascular Disease

Eidelman RS, Hebert PR, Weisman SM, Hennekens, CH.
Arch Intern Med.   2003;163:2006-2010.
  KEYWORDS: Aspirin , CVD , MI
 
Click for Full Abstract

Effects of Comprehensive Lifestyle Modification on Diet, Weight, Physical Fitness, and Blood Pressure Control: 18-Month Results of a Randomized Trial

Elmer PJ, Obarzanek E, Vollmer WM, et al, for the PREMIER Collaborative Research Group.
Ann Intern Med.  2006;144:485-495.
  KEYWORDS: Diet , Hypertension
 
Click for Full Abstract

Cardiovascular Disease and Subsequent Kidney Disease

Elsayed EF, Tighiouart H, Griffith J, et al.
Arch Intern Med.  2007;167(11):1130-1136.
  KEYWORDS: CVD , Diabetes , Hypertension

Impact of Infectious Burden on Extent and Long-Term Prognosis of Atherosclerosis

Espinola-Klein C, Rupprecht HJ, Blankenberg S, et al.
Circulation.  2002;105:15-21.
  KEYWORDS: Atherosclerosis , Infection
 
Click for Full Abstract

Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)

Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.
JAMA.  2001;285:2486-2497.
  KEYWORDS: ATP III , CHD , Framingham Heart Study , LDL-C

Plasma Triglycerides and Cardiovascular Events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering Trials of Statins in Patients with Coronary Artery Disease

Faergeman O, Holme I, Fayyad R, et al.
Am J Cardiol.  2009;104(4):459-463.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor , Triglycerides
 
Click for Full Abstract

Plasma Triglycerides and Cardiovascular Events in the Treating to New Targets and Incremental Decrease in End-Points Through Aggressive Lipid Lowering Trials of Statins in Patients with Coronary Artery Disease

Faergeman O, Holme I, Fayyad R, et al; for the Steering Committees of the IDEAL and TNT Trials
Am J Cardiol.  2009;104(4):459-463.
  KEYWORDS: Triglycerides

New National Cholesterol Education Program III Guidelines for Primary Prevention Lipid-Lowering Drug Therapy: Projected Impact on the Size, Sex, and Age Distribution of the Treatment-Eligible Population

Fedder DO, Koro CE, L`Italien GJ.
Circulation.  2002;105:152-156.
  KEYWORDS: ATP III , LDL-C
 
Click for Full Abstract

A Review of Simple, Non-Invasive Means of Assessing Peripheral Arterial Disease and Implications for Medical Management

Ferreira AC, Macedo FY.
Ann Med.  2010;42(2):139-150.
  KEYWORDS: PAD
 
Click for Full Abstract

IRAS: Insulin Resistance Atherosclerosis Study
 Chronic Subclinical Inflammation as Part of the Insulin Resistance Syndrome: The Insulin Resistance Atherosclerosis Study

Festa A, D`Agostino R, Howard G, Mykkanen L, Tracy R, Haffner SM.
Circulation.  2000;102:42-47.
  KEYWORDS: Inflammation , Insulin resistance
 
Click for Full Abstract

National, Regional, and Global Trends in Body-mass Index since 1980: Systematic Analysis of Health Examination Surveys and Epidemiological Studies with 960 Country-years and 9.1 million Participants

Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M
Lancet  2011;377(9765):557-567.
  KEYWORDS: BMI , Obesity/overweight , Risk assessment
 
Click for Full Abstract

US Multicenter Experience With the Wingspan Stent System for the Treatment of Intracranial Atheromatous Disease: Periprocedural Results

Fiorella D, Levy EI, Turk AS, et al.
Stroke.  2007;38:881-887.
  KEYWORDS: Revascularization

CARE: Cholesterol and Recurrent Events
 Pravastatin Prevents Clinical Events in Revascularized Patients With Average Cholesterol Concentrations

Flaker GC, Warnica JW, Sacks FM, et al, for the Cholesterol and Recurrent Events CARE Investigators.
J Am Coll Cardiol.  1999;34:106-112.
  KEYWORDS: CABG , CAD , HMG-CoA reductase inhibitor , MI , Revascularization
 
Click for Full Abstract

Mechanical Thrombectomy of Intracranial Internal Carotid Occlusion: Pooled Results of the MERCI and Multi MERCI Part I Trials

Flint AC, Duckwiler GR, Budzik RF, Liebeskind DS, Smith WS, for the MERCI and Multi MERCI Writing Committee.
Stroke.  2007;38:1274-1280.
  KEYWORDS: Revascularization

NRMI: National Registry of Myocardial Infarction
 Use of Lipid-Lowering Medications at Discharge in Patients With Acute Myocardial Infarction: Data From the National Registry of Myocardial Infarction 3

Fonarow GC, French WJ, Parsons LS, Haili S, Malmgren JA, for the National Registry of Myocardial Infarction 3 Participants.
Circulation.  2001;103:38-44.
  KEYWORDS: MI
 
Click for Full Abstract

Effect of Statin Use Within the First 24 Hours of Admission for Acute Myocardial Infarction on Early Morbidity and Mortality

Fonarow GC, Wright RS, Spencer FA, et al, for the National Registry of Myocardial Infarction 4 Investigators.
Am J Cardiol.  2005;96:611-616.
  KEYWORDS: HMG-CoA reductase inhibitor , MI
 
Click for Full Abstract

Endothelial and Erectile Dysfunction, Diabetes Mellitus, and the Metabolic Syndrome: Common Pathways and Treatments?

Fonseca V, Jawa A.
Am J Cardiol.   2005;96(suppl 2):13M-18M.
  KEYWORDS: CVD , Diabetes , Metabolic Syndrome

Colesevelam HCL Added To Sulfonylurea (SU)-Based Therapy in Patients With Inadequately Controlled Type 2 Diabetes Mellitus (T2DM) Improves Glycemic Control

Fonseca VA, Rosenstock J, Truitt K, Dmuchowski C, Jones M.

 

  KEYWORDS: Diabetes

Trends in the Risk for Coronary Heart Disease Among Adults with Diagnosed Diabetes in the U.S.: Findings from the National Health and Nutrition Examination Survey, 1999-2008

Ford ES
Diabetes Care  2011 Apr 19. [Epub ahead of print]
  KEYWORDS: CHD , Diabetes , Framingham Heart Study
 
Click for Full Abstract

Prevalence of the Metabolic Syndrome Among US Adults: Findings from the Third National Health and Nutrition Examination Survey

Ford ES, Giles WH, Dietz WH.
JAMA.  2002;287:356-359.
  KEYWORDS: ATP III , Metabolic Syndrome

Serum Total Cholesterol Concentrations and Awareness, Treatment, and Control of Hypercholesterolemia Among US Adults

Ford ES, Mokdad AH, Giles WH, Mensah GA.
Circulation.  2003;107:2185-2189.
  KEYWORDS: CHD
 
Click for Full Abstract

WOSCOPS: West of Scotland Coronary Prevention Study
 Pravastatin and the Development of Diabetes Mellitus: Evidence for a Protective Treatment Effect in the West of Scotland Coronary Prevention Study

Freeman DJ, Norrie J, Sattar N, et al.
Circulation.  2001;103:357-362.
  KEYWORDS: Diabetes , HMG-CoA reductase inhibitor
 
Click for Full Abstract

ALLHAT: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
 Major Outcomes in Moderately Hypercholesterolemic, Hypertensive Patients Randomized to Pravastatin vs Usual Care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)

Furberg CD, Wright JT, Davis BR, et al, for the ALLHAT Collaborative Research Group.
JAMA.  2002;288:2998-3007.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , Hypertension , Older adults

Steno-2 Study
 Multifactorial Intervention and Cardiovascular Disease in Patients with Type 2 Diabetes

Gaede P, Vedel P, Larsen N, Jensen GVH, Parving HH, Pedersen O.
N Engl J Med.  2003;348:383-393.
  KEYWORDS: CVD , Diabetes , Hypertension

Efficacy and Safety of Ezetimibe Added to Ongoing Statin Therapy for Treatment of Patients With Primary Hypercholesterolemia

Gagné C, Bays HE, Weiss SR, et al, for the Ezetimibe Study Group.
Am J Cardiol.  2002;90:1084-1091.
  KEYWORDS: Combination therapy , Ezetimibe , HMG-CoA reductase inhibitor , LDL-C

Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial

Galan P, Kesse-Guyot E, Czernichow S, et al, for the SU.FOL.OM3 Collaborative Group.
BMJ.   2010;c6273.
  KEYWORDS: Omega-3 polyunsaturated fatty acids

Cost-Effectiveness of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor Therapy in Older Patients with Myocardial Infarction

Ganz DA, Kuntz KM, Jacobson GA, Avorn J.
Ann Int Med.  2000;132:780-787.
  KEYWORDS: Cost-effectiveness , MI , Older adults
 
Click for Full Abstract

Erectile Dysfunction: Pathophysiologic Mechanisms Pointing to Underlying Cardiovascular Disease

Ganz P.
Am J Cardiol.   2005;96(suppl 2):8M-12M.
  KEYWORDS: Atherosclerosis , CVD , Diabetes , Endothelium , Insulin resistance , Metabolic Syndrome

Statin Therapy and Risks for Death and Hospitalization in Chronic Heart Failure

Go AS, Lee WY, Yang J, Lo JC, Gurwitz JH.
JAMA.  2006;296:2105-2111.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor

Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: the diet, obesity, and genes (DiOGenes) study: a randomized, controlled trial

Gögebakan O, Kohl A, Osterhoff MA, van Baak MA, Jebb SA, Papadaki A, et al.
Circulation  2011;124(25):2829-2838. Epub 2011 Nov 21.
  KEYWORDS: CRP , Diet , HDL-C , LDL-C , Obesity/overweight , Risk assessment , Triglycerides

Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults

Goodpaster BH, DeLany JP, Otto AD, et al.
JAMA.   2010;304(16):1795-1802.
  KEYWORDS: Diet , Exercise

Lowering LDL Cholesterol: Questions From Recent Meta-Analyses and Subset Analyses of Clinical Trial Data Issues From the Interdisciplinary Council on Reducing the Risk for Coronary Heart Disease, Ninth Council Meeting

Gotto AM Jr, Grundy SM.
Circulation.  1999;99:E1-E7.
  KEYWORDS: CHD , LDL-C


Click for Full Abstract

Cardiovascular and Cancer Mortality in Very Elderly Post-Myocardial Infarction Patients Receiving Statin Treatment

Gränsbo K, Melander O, Wallentin L, et al.
J Am Coll Cardiol.   2010;55(13):1362-1369.
  KEYWORDS: HMG-CoA reductase inhibitor , MI , Older adults
 
Click for Full Abstract

Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines

Grundy SM, Cleeman JI, Merz CNB, et al, for the Coordinating Committee of the National Cholesterol Education Program.
Circulation.  2004;110:227-239.
  KEYWORDS: ATP III , CHD , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

Cardiovascular and Metabolic Risk Factors: How Can We Improve Outcomes in the High-Risk Patient?

Grundy SM.
Am J Med.  2007;120(9A):S3-S9.
  KEYWORDS: ATP III , CHD , Diabetes , LDL-C , Metabolic Syndrome

Dyslipidemia and the Risk of Incident: Hypertension in Men

Halperin RO, Sesso HD, Ma J, Buring JE, Stampfer MJ, Gaziano JM.
Hypertension.  2006;47:45-50.
  KEYWORDS: CVD , HDL-C , Hypertension
 
Click for Full Abstract

Usefulness of Omega-3 Fatty Acids and the Prevention of Coronary Heart Disease

Harper CR, Jacobson TA.
Am J Cardiol.  2005;96:1521-1529.
  KEYWORDS: CHD , Omega-3 polyunsaturated fatty acids
 
Click for Full Abstract

Optimizing Statin Treatment for Primary Prevention of Coronary Artery Disease

Hayward RA, Krumholz HM, Zulman DM, Timbie JW, Vijan S.
Ann Intern Med.   2010 Jan 19;152(2):69-77.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor
 
Click for Full Abstract

Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults

He K, Liu K, Daviglus ML, et al.
Circulation.  2006;113:1675-1682.
  KEYWORDS: Metabolic Syndrome

Preprocedural Statin Medication Reduces the Extent of Periprocedural Non–Q-Wave Myocardial Infarction

Herrmann J, Lerman A, Baumgart D, et al.
Circulation.  2002;106:2180-2183.
  KEYWORDS: HMG-CoA reductase inhibitor , MI , Stents


Click for Full Abstract

EPAT
 Estrogen in the Prevention of Atherosclerosis–A Randomized, Double-Blind, Placebo-Controlled Trial

Hodis HN, Mack WJ, Lobo RA, et al.
Ann Intern Med.  2001;135:939-953.
  KEYWORDS: Atherosclerosis , HRT , Women
 
Click for Full Abstract

RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes trial.
 Rosiglitazone Evaluated for Cardiovascular Outcomes—An Interim Analysis

Home PD, Pocock SJ, Beck-Nielsen H, et al, for the RECORD Study Group.
N Eng J Med.  2007;357(1):28-38.
  KEYWORDS: Diabetes

Rosiglitazone Evaluated for Cardiovascular Outcomes in Oral Agent Combination Therapy for Type 2 Diabetes (RECORD): A Multicentre, Randomized, Open-Label Trial

Home PD, Pocock SJ, Beck-Nielsen H, et al; for the RECORD Study Team.
Lancet.  2009;373(9681):2125-2135.
  KEYWORDS: Diabetes

Post CABG: Post Coronary Artery Bypass Graft
 Effects of Aggressive Cholesterol Lowering and Low-dose Anticoagulation on Clinical and Angiographic Outcomes in Patients With Diabetes: the Post Coronary Artery Bypass Graft Trial

Hoogwerf BJ, Waness A, Cressman M, et al, for the Post CABG Study Investigators.
Diabetes.  1999;48:1289-1294.
  KEYWORDS: CABG , CHD , Diabetes , Post CABG
 
Click for Full Abstract

Plasma Triglycerides and Type III Hyperlipidemia are Independently Associated With Premature Familial Coronary Artery Disease

Hopkins PN, Wu LL, Hunt SC, Brinton EA.
J Am Coll Cardiol.  2005;45:1003-1012.
  KEYWORDS: CAD , HDL-C

Statin Therapy, Lipid Levels, C-Reactive Protein and the Survival of Patients With Angiographically Severe Coronary Artery Disease

Horne BD, Muhlestein JB, Carlquist JF, et al.
J Am Coll Cardiol.  2000;36:1774-1780.
  KEYWORDS: CAD , CRP , HMG-CoA reductase inhibitor

 
Click for Full Abstract

Statin Therapy Is Associated With Improved Survival in Ischemic and Non-Ischemic Heart Failure

Horwich TB, MacLellan WR, Fonarow GC.
J Am Coll Cardiol.   2004;43:642-648.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor
 
Click for Full Abstract

Prevention of Atherosclerosis with Low-Density Lipoprotein Cholesterol—Lowering Lipoprotein Changes and Interactions: The SANDS Study

Howard WJ, Russell M, Fleg JL, et al.
J Clin Lipidol.  2009;3(5):322-331.
  KEYWORDS: CIMT , LDL-C
 
Click for Full Abstract

Impact of Dietary n-3 Fatty Acid and Statins on HDL and Total Cholesterol Levels in US Adults: An Analysis of the 1999–2002 National Health and Nutrition Examination Survey

Hui JK, Lipsitz S, Natarajan S.

 

  KEYWORDS: Combination therapy , HDL-C , HMG-CoA reductase inhibitor , Omega-3 polyunsaturated fatty acids

AIR: Atherosclerosis and Insulin Resistance
 The Metabolic Syndrome, LDL Particle Size, and Atherosclerosis. The Atherosclerosis and Insulin Resistance (AIR) Study

Hulthe J, Bokemark L, Wikstrand J, Fagerberg B.
Arterioscler Thromb Vasc Biol.  2000;20:2140-2147.
  KEYWORDS: Atherosclerosis , Metabolic Syndrome
 
Click for Full Abstract

A Dose-Ranging Study of a New, Once-Daily, Dual-Component Drug Product Containing Niacin Extended-Release and Lovastatin

Hunninghake DB, McGovern ME, Koren M, et al.
Clin Cardiol.  2003;26:112-118.
  KEYWORDS: Combination therapy , HDL-C , LDL-C


Click for Full Abstract

Postdischarge Lipid Management of Coronary Artery Disease Patients According to the New National Cholesterol Education Program Guidelines

Hunninghake DB.
Am J Cardiol.  2001;88(suppl):37K-41K.
  KEYWORDS: ATP III

Isolated low levels of high-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease: an individual participant data meta-analysis of 23 studies in the Asia-Pacific region

Huxley RR, Barzi F, Lam TH, Czernichow S, Fang X, Welborn T, Shaw J, Ueshima H, Zimmet P, Jee SH, Patel JV, Caterson I, Perkovic V, Woodward M; for the Asia Pacific Cohort Studies Collaboration and the Obesity in Asia Collaboration.
Circulation.   2011 Oct 10. [Epub ahead of print]
  KEYWORDS: CHD , HDL-C
 
Click for Full Abstract

Cigarette smoking as a risk factor for coronary heart disease in women compared with men: a systematic review and meta-analysis of prospective cohort studies

Huxley RR, Woodward M.
Lancet.   2011;378(9799):1297-1305.
  KEYWORDS: CHD , Women
 
Click for Full Abstract

ACCOMPLISH: Avoiding Cardiovascular events through COMbination therapy in Patients LIving with Systolic Hypertension trial
 Exceptional Early Blood Pressure Control Rates: The ACCOMPLISH Trial

Jamerson K, Bakris GL, Dahlöf B, et al, for the ACCOMPLISH Investigators.

 

  KEYWORDS: Combination therapy , Diabetes , Hypertension

Elevated High-Density Lipoprotein Cholesterol Levels Are Protective Against Plaque Progression: A Follow-Up Study of 1952 Persons With Carotid Atherosclerosis – TheTromsø Study

Johnsen SH, Mathiesen EB, Fosse E, et al.
Circulation.  2005;112:498-504.
  KEYWORDS: Carotid atherosclerosis , HDL-C
 
Click for Full Abstract

Efficacy and Safety of Fenofibric Acid Co-Administered With Low- or Moderate-Dose Statin in Patients With Mixed Dyslipidemia and Type 2 Diabetes Mellitus: Results of a Pooled Subgroup Analysis From Three Randomized, Controlled, Double-Blind Trials

Jones PH, Cusi K, Davidson MH, et al.
Am J Cardiovasc Drugs.  2010;10(2):73-84.
  KEYWORDS: Diabetes , Fibric acid , HMG-CoA reductase inhibitor
 
Click for Full Abstract

Comparison of Efficacy and Safety of Atorvastatin and Simvastatin in Patients With Dyslipidemia With and Without Coronary Heart Disease

Karalis DG, Ross AM, Vacari RM, Zarren H, Scott R, on behalf of the CHALLENGE Study Investigators.
Am J Cardiol.  2002;89:667-671.
  KEYWORDS: CHD , HDL-C , HMG-CoA reductase inhibitor , LDL-C , Triglycerides
 
Click for Full Abstract

ENHANCE: Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression
 Simvastatin With or Without Ezetimibe in Familial Hypercholesterolemia

Kastelein JJP, Akdim F, Stroes ESG, et al.
N Engl J Med.  2008;358(14):1431-1443.
  KEYWORDS: Atherosclerosis , CIMT , Combination therapy , HMG-CoA reductase inhibitor , LDL-C

FIELD: Fenofibrate Intervention and Event Lowering in Diabetes
Effects of Long-Term Fenofibrate Therapy on Cardiovascular Events in 9795 People With Type 2 Diabetes Mellitus (the FIELD Study): Randomised Controlled Trial

Keech A, Simes RJ, Barter P, et al, for the FIELD Study Investigators.
Lancet.  2005;366:1849-1861.
  KEYWORDS: CVD , Diabetes , Fibric acid
 
Click for Full Abstract

Implications of Cardiac Risk and Low-Density Lipoprotein Cholesterol Distributions in the United States for the Diagnosis and Treatment of Dyslipidemia: Data from National Health and Nutrition Examination Survey 1999 to 2002

Keevil JG, Cullen MW, Gangnon R, McBride PE, Stein JH.
Circulation.  2007;115(11):1363-1370.
  KEYWORDS: ATP III , CHD , LDL-C

Association of C-reactive protein with cardiovascular disease mortality according to diabetes status: pooled analyses of 25,979 participants from four U.K. prospective cohort studies.

Kengne AP, Batty GD, Hamer M, Stamatakis E, Czernichow S.
Diabetes Care.  2012;35(2):396-403. Epub 2011 Dec 30.
  KEYWORDS: CRP , CVD , Diabetes , HMG-CoA reductase inhibitor , Statins

Vitamin D, parathyroid hormone, and cardiovascular events among older adults.

Kestenbaum B, Katz R, de Boer I, Hoofnagle A, Sarnak MJ, Shlipak MG, Jenny NS, Siscovick DS.
J Am Coll Cardiol.   2011;58(14):1433-1441.
  KEYWORDS: Coronary artery assessment , Smoking
 
Click for Full Abstract

Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

Khera AV, Cuchel M, de la Llera-Moya M, Rodrigues A, Burke MF, Jafri K, French BC, Phillips JA, Mucksavage ML, Wilensky RL, Mohler ER, Rothblat GH, Rader DJ.
N Engl J Med.  2011;364(2):127-135.
  KEYWORDS: Atherosclerosis , HDL-C
 
Click for Full Abstract

MIRACL: Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering
 High-Dose Atorvastatin Enhances the Decline in Inflammatory Markers in Patients With Acute Coronary Syndromes in the MIRACL Study

Kinlay S, Schwartz GG, Olsson AG, et al, for the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators
Circulation.  2003;108:1560-1566.
  KEYWORDS: CRP , HMG-CoA reductase inhibitor , Inflammation , MI

Click for Full Abstract

Effect of Aerobic Exercise Training on Serum Levels of High-Density Lipoprotein Cholesterol: a Meta-Analysis

Kodama S, Tanaka S, Saito K, et al.
Arch Intern Med.  2007;167(10):999-1008.
  KEYWORDS: BMI , HDL-C , MI

Additive Beneficial Effects of Fenofibrate Combined With Atorvastatin in the Treatment of Combined Hyperlipidemia

Koh KK, Quon MJ, Han SH, et al.
J Am Coll Cardiol.  2005;45:1649-1653.
  KEYWORDS: Combination therapy , CRP , HMG-CoA reductase inhibitor , Metabolic Syndrome
 
Click for Full Abstract

Statin Attenuates Increase in C-Reactive Protein During Estrogen Replacement Therapy in Postmenopausal Women

Koh KK, Schenke WH, Waclawiw MA, Csako G, Cannon RO III.
Circulation.  2002;105:1531-1533.
  KEYWORDS: HMG-CoA reductase inhibitor , HRT , Women
 
Click for Full Abstract

ALLIANCE: Aggressive Lipid-Lowering Initiation Abates New Cardiac Events
 Clinical Outcomes in Managed-Care Patients With Coronary Heart Disease Treated Aggressively in Lipid-Lowering Disease Management Clinics: The ALLIANCE Study

Koren MJ, Hunninghake DB, on behalf of the ALLIANCE Investigators
J Am Coll Cardiol.   2004;44:1772-1779.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

Meta-analysis of statin effects in women versus men

Kostis WJ, Cheng JQ, Dobrzynski JM, Cabrera J, Kostis JB.
J Am Coll Cardiol  2012;59(6):572-582.
  KEYWORDS: HMG-CoA reductase inhibitor , Statins , Women

Separate Effects of Reduced Carbohydrate Intake and Weight Loss on Atherogenic Dyslipidemia

Krauss RM, Blanche PJ, Rawlings RS, Fernstrom HS, Williams PT.
Am J Clin Nutr.   2006;83:1025-1031.
  KEYWORDS: Diet , HDL-C , LDL-C , Obesity/overweight
 
Click for Full Abstract

MESA: Multi-Ethnic Study of Atherosclerosis
 Risk Factors for the Progression of Coronary Artery Calcification in Asymptomatic Subjects: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)

Kronmal RA, McClelland RL, Detrano R, et al.
Circulation.   2007;115(21):2722-2730.
  KEYWORDS: Atherosclerosis

Antiplatelets, ACE Inhibitors, and Statins Combination Reduces Stroke Severity and Tissue at Risk

Kumar S, Savitz S, Schlaug G, Caplan L, Selim M.
Neurology.  2006;66:1153-1158.
  KEYWORDS: Combination therapy , HMG-CoA reductase inhibitor

Migraine and Risk of Cardiovascular Disease in Women

Kurth T, Gaziano JM, Cook NR, Logroscino G, Diener H-C, Buring JE.
JAMA.  2006;296:283-291.
  KEYWORDS: CVD , MI , Women

Inhibition of Clinical Benefits of Aspirin on First Myocardial Infarction by Nonsteroidal Antiinflammatory Drugs

Kurth T, Glynn RJ, Walker AM, et al.
Circulation.  2003;108:1191-1195.
  KEYWORDS: Aspirin , MI
 
Click for Full Abstract

Differences in Serum Sex Hormone and Plasma Lipid Levels in Caucasian and African-American
Premenopausal Women

Lamon-Fava S, Barnett JB, Woods MN, et al.
J Clin Endocrinol Metab.  2005;90(8):4516-45120.
  KEYWORDS: BMI , CHD , HDL-C , Triglycerides , Women

TNT: Treating to New Targets
 Intensive Lipid Lowering With Atorvastatin in Patients With Stable Coronary Disease

LaRosa JC, Grundy SM, Waters DD, et al, for the Treating to New Targets (TNT) Investigators
N Engl J Med.   2005;352:1425-1435.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , LDL-C

Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Diseases

Lavie CJ, Milani RV, Mehra MR, Ventura HO.
J Am Coll Cardiol.  2009;54(7):585-594.
  KEYWORDS: CVD , Omega-3 polyunsaturated fatty acids
 
Click for Full Abstract

Impact of Diabetes on Coronary Artery Disease in Women and Men

Lee WL, Cheung AM, Cape D, Zinman B.
Diabetes Care.  2000;23:962-968.
  KEYWORDS: CAD , Diabetes
 
Click for Full Abstract

Cardiovascular Health Study
 Therapy With Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors (Statins) and Associated Risk of Incident Cardiovascular Events in Older Adults—Evidence From the Cardiovascular Health Study

Lemaitre RN, Psaty BM, Heckbert SR, Kronmal RA, Newman AB, Burke GL.
Arch Intern Med.  2002;162:1395-1400.
  KEYWORDS: HMG-CoA reductase inhibitor , Older adults
 
Click for Full Abstract

Blood Cholesterol and Vascular Mortality by Age, Sex, and Blood Pressure: A Meta Analysis of Individual Data From 61 Prospective Studies With 55000 Vascular Deaths.

Lewington S, Whitlock G, Clarke R, et al, for the Prospective Studies Collaboration Committee.
Lancet.  2007;370(9602):1829-1839.
  KEYWORDS: HDL-C , Hypertension

Behavioral counseling to promote physical activity and a healthful diet to prevent cardiovascular disease in adults: a systematic review for the U.S. Preventive Services Task Force

Lin JS, O'Connor E, Whitlock EP, Beil TL.
Ann Intern Med.  2010;153(11):736-750.
  KEYWORDS: CVD , Diet , Exercise
 
Click for Full Abstract

Pioglitazone and Risk of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Trials

Lincoff AM, Wolski K, Nicholls SJ, Nissen SE.
JAMA.  2007;298(10):1180-1188.
  KEYWORDS: Diabetes , MI

Joint Distribution of Non-HDL and LDL Cholesterol and Coronary Heart Disease Risk Prediction Among Individuals With and Without Diabetes

Liu J, Sempos C, Donahue RP, Dorn J, Trevisan M, Grundy SM.
Diabetes Care.  2005;28:1916-1921.
  KEYWORDS: CHD , Diabetes , HDL-C , LDL-C
 
Click for Full Abstract

The ARIC Study: The Atherosclerosis Risk in Communities Study
 Waist–Hip Ratio as a Predictor of Incident Hospitalized Heart Failure: The ARIC Study

Loehr LR, Rosamond WD, Chang PP, et al.

 

  KEYWORDS: BMI , MI , Obesity/overweight

Diet and Risk of Coronary Heart Disease and Type 2 Diabetes

Mann JI.
Lancet.  2002;360:783-789.
  KEYWORDS: CHD , Diabetes , Diet
 
Click for Full Abstract

Suita Study
 Strong and Significant Relationships Between Aggregation of Major Coronary Risk Factors and the Acceleration of Carotid Atherosclerosis in the General Population of a Japanese City. The Suita Study

Mannami T, Baba S, Ogata J.
Arch Int Med.  2000;160:2297-2303.
  KEYWORDS: Carotid atherosclerosis , CIMT
 
Click for Full Abstract

Estrogen plus Progestin and the Risk of Coronary Heart Disease

Manson JE, Hsia J, Johnson KC, et al, for the Women’s Health Initiative Investigators
N Engl J Med.   2003;349:523-534.
  KEYWORDS: CHD , HRT , Women

GISSI-Prevenzione: Gruppo Italiano per lo Studio della Sopravvivenza nell`Infarto Miocardico
 Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction: Time-Course Analysis of the Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell`Infarto Miocardico (GISSI)-Prevenzione

Marchioli R, Barzi F, Bomba E, et al, on behalf of the GISSI-Prevenzione Investigators.
Circulation.  2002;105:1897-1903.
  KEYWORDS: Diet , MI , Omega-3 polyunsaturated fatty acids

The Nurse Practitioner’s Role in Helping Patients Achieve Lipid Goals With Statin Therapy

Mason CM.
J Am Acad Nurse Pract.  2005;17:256-262.
  KEYWORDS: CHD , LDL-C

KEEP: Kidney Early Evaluation Program
 Independent Components of Chronic Kidney Disease as a Cardiovascular Risk State: Results from the Kidney Early Evaluation Program (KEEP)

McCullough PA, Jurkovitz CT, Pergola PE, et al, for the KEEP Investigators
Arch Intern Med.  2007;167(11):1122-1129.
  KEYWORDS: CVD , Diabetes

Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies

McGettigan P, Henry D.
PLoS Med.   2011;8(9):e1001098.
  KEYWORDS: CVD , Risk assessment

Metabolic Syndrome and Risk of Acute Myocardial Infarction: A Case-Control Study of 26,903 Subjects from 52 Countries

Mente A, Yusuf S, Islam S, et al; for the INTERHEART Investigators.
J Am Coll Cardiol.  2010;55(21):2390-2398.
  KEYWORDS: Metabolic Syndrome
 
Click for Full Abstract

Cost-effectiveness of Simvastatin in People at Different Levels of Vascular Disease Risk: Economic Analysis of a Randomised Trial in 20,536 Individuals

Mihaylova B, Briggs A, Armitage J, Parish S, Gray A, Collins R, for the Heart Protection Study Collaborative Group.
Lancet.  2005;365:1779-1785.
  KEYWORDS: Cost-effectiveness , CVD , Diabetes , HMG-CoA reductase inhibitor


Click for Full Abstract

Triglycerides and cardiovascular disease: A scientific statement from the American Heart Association

Miller M, Stone NJ, Ballantyne C, et al; on behalf of the American Heart Association Clinical Lipidology, Thrombosis, and Prevention Committee of the Council on Nutrition, Physical Activity, and Metabolism, Council on Arteriosclerosis, Thrombosis and Vascular Biology, Council on Cardiovascular Nursing, and Council on the Kidney in Cardiovascular Disease.
Circulation.   2011;123(20):2292-2333.
  KEYWORDS: Triglycerides
 
Click for Full Abstract

High Attributable Risk of Elevated C-Reactive Protein Level to Conventional Coronary Heart Disease Risk Factors: The Third National Health and Nutrition Examination Survey

Miller M, Zhan M, Havas S.
Arch Intern Med.  2005;165:2063-2068.
  KEYWORDS: CHD , CRP


Click for Full Abstract

Cholesterol Reduction With Atorvastatin Improves Walking Distance in Patients With Peripheral Arterial Disease

Mohler III ER, Hiatt WR, Creager MA, for the Study Investigators
Circulation.  2003;108:1481-1486.
  KEYWORDS: Atherosclerosis , HMG-CoA reductase inhibitor , PAD

 
Click for Full Abstract

Physical Activity and Reduced Risk of Cardiovascular Events: Potential Mediating Mechanisms

Mora S, Cook N, Buring JE, Ridker PM, Lee IM.
Circulation.  2007;116(19):2110-2118.
  KEYWORDS: CVD , Exercise , HDL-C , Hypertension , LDL-C

Statins for the Primary Prevention of Cardiovascular Events in Women With Elevated High-Sensitivity C-Reactive Protein or Dyslipidemia. Results From the JUPITER Trial and Meta Analysis of Women From Primary Prevention Trials

Mora S, Glynn RJ, Hsia J, MacFadyen JG, Genest J, Ridker PM
Circulation.  2010;121(9):1069-1077.
  KEYWORDS: CRP , CVD , HMG-CoA reductase inhibitor , LDL-C , MI , Women

Association of Physical Activity and Body Mass Index With Novel and Traditional Cardiovascular Biomarkers in Women

Mora S, Lee IM, Buring JE, Ridker PM.
JAMA.  2006:295;1412-1419.
  KEYWORDS: Atherosclerosis , BMI , CVD , Diet , Inflammation , MI , Women

Opportunity for Intervention to Achieve American Heart Association Guidelines for Optimal Lipid Levels in High-Risk Women in a Managed Care Setting

Mosca L, Bairey Merz N, Blumenthal RS, et al.
Circulation.   2005;111:488-493.
  KEYWORDS: Combination therapy , CVD , HDL-C , HMG-CoA reductase inhibitor , LDL-C , Women

 
Click for Full Abstract

Guide to Preventive Cardiology for Women. AHA/ACC Scientific Statement: Consensus Panel Statement

Mosca L, Grundy SM, Judelson D, et al.
Circulation.1999;99:2480-2484.
J Am Coll Cardiol.1999;33:1751-1755. 
1999;99:2480-2484.
Journal of the American College of Cardiology.
1999;33:1751-1755.
  KEYWORDS: CHD , HDL-C , Women

The Metabolic Syndrome and Cardiovascular Risk: A Systematic Review and Meta-Analysis

Mottillo S, Filion KB, Genest J, et al.
J Am Coll Cardiol.  2010;56(14):1113-1132.
  KEYWORDS: CVD , Metabolic Syndrome

Usefulness of In-Hospital Prescription of Statin Agents After Angiographic Diagnosis of Coronary Artery Disease in Improving Continued Compliance and Reduced Mortality

Muhlestein JB, Horne BD, Bair TL, et al.
Am J Cardiol.  2001;87:257-261.
  KEYWORDS: Angiography , CAD , HMG-CoA reductase inhibitor
 
Click for Full Abstract

The Importance of Early Diagnosis and Treatment in Peripheral Arterial Disease: Insights From the PARTNERS and REACH Registries

Mukherjee D, Eagle K.
Curr Vasc Pharmacol.   20101;8(3):293-300.
  KEYWORDS: PAD
 
Click for Full Abstract

REGRESS: Regression Growth Evaluation Statin Study
 Pravastatin Reduces Restenosis Two Years After Percutaneous Transluminal Coronary Angioplasty (REGRESS Trial)

Mulder HJGH, Bal ET, Jukema JW, et al.
Am J Cardiol.   2000;86:742-746.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor


Click for Full Abstract

Coronary Artery Calcification and Family History of Premature Coronary Heart Disease: Sibling History Is More Strongly Associated Than Parental History

Nasir K, Michos ED, Rumberger JA, et al.
Circulation.  2004;110:2150-2156.
  KEYWORDS: Atherosclerosis , CHD , Family history
 
Click for Full Abstract

Safety of Atorvastatin Derived from Analysis of 44 Completed Trials in 9,416 Patients

Newman CB, Palmer G, Silbershatz H, Szarek M.
Am J Cardiol.   2003;92:670-676.
  KEYWORDS: HMG-CoA reductase inhibitor

Effect of two intensive statin regimens on progression of coronary disease.

Nicholls SJ, Ballantyne CM, Barter PJ, Chapman MJ, Erbel RM, Libby P, Raichlen JS, Uno K, Borgman M, Wolski K, Nissen SE.
N Engl J Med.   2011;365(22):2078-2087. Epub 2011 Nov 15.
  KEYWORDS: Atherosclerosis , HDL-C , LDL-C , Statins

Effects of Obesity on Lipid-Lowering, Anti-Inflammatory, and Antiatherosclerotic Benefits of Atorvastatin or Pravastatin in Patients With Coronary Artery Disease: from the REVERSAL Study

Nicholls SJ, Tuzcu EM, Sipahi I, et al.
Am J Cardiol.   2006;97:1553-1557.
  KEYWORDS: Atherosclerosis , BMI , CAD , HMG-CoA reductase inhibitor , Inflammation , MI , Obesity/overweight
 
Click for Full Abstract

Statins, High-Density Lipoprotein Cholesterol, and Regression of Coronary Atherosclerosis

Nicholls SJ, Tuzcu EM, Sipahi I, et al.
JAMA.  2007;297(5):499-508.
  KEYWORDS: Atherosclerosis , CAD , HDL-C , HMG-CoA reductase inhibitor , LDL-C

Change in high-density lipoprotein cholesterol and risk of subsequent hospitalization for coronary artery disease or stroke among patients with type 2 diabetes mellitus

Nichols GA, Vupputuri S, Rosales AG.
Am J Cardiol.   2011;108(8):1124-1128.
  KEYWORDS: CAD , Diabetes , HDL-C , Stroke
 
Click for Full Abstract

Association of the Metabolic Syndrome With History of Myocardial Infarction and Stroke in the Third National Health and Nutrition Examination Survey

Ninomiya JK, L’Italien G, Criqui MH, Whyte JL, Gamst A, Chen RS.
Circulation.  2004;109:42-46.
  KEYWORDS: Diabetes , HDL-C , Hypertension , Insulin resistance , Metabolic Syndrome , MI
 
Click for Full Abstract

ASTEROID: A Study to Evaluate the Effect of Rosuvastatin on Intravascular Ultrasound-Derived Coronary Atheroma Burden
Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial

Nissen SE, Nicholls SJ, Sipahi I, et al, for the ASTEROID Investigators.
JAMA.  2006;295:1556-1565.
  KEYWORDS: Atherosclerosis , HMG-CoA reductase inhibitor , LDL-C

Effect of Recombinant ApoA-1 Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes: A Randomized Controlled Trial

Nissen SE, Tsunoda T, Tuzcu EM, et al.
JAMA.   2003;290:2292-2300.
  KEYWORDS: Atherosclerosis , HDL-C

Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease

Nissen SE, Tuzcu EM, Schoenhagen P, et al, for the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) Investigators.
N Engl J Med.   2005;352:29-38.
  KEYWORDS: CAD , CRP , HMG-CoA reductase inhibitor , Inflammation , LDL-C , MI

REVERSAL: Reversal of Atherosclerosis with Aggressive Lipid Lowering trial
 Effect of Intensive Compared With Moderate Lipid-Lowering Therapy on Progression of Coronary Atherosclerosis: A Randomized Controlled Trial

Nissen SE, Tuzcu EM, Schoenhagen P, et al.
JAMA.  2004;291:1071-1080.
  KEYWORDS: Atherosclerosis , CRP , HMG-CoA reductase inhibitor , LDL-C

Primary and Secondary Prevention of Cardiovascular Diseases: A Practical Evidence-Based Approach

O’Keefe JH, Carter MD, Lavie CJ.
Mayo Clin Proc.  2009;84(8):741-757.
  KEYWORDS: CHD , Combination therapy , CVD , Diet , Exercise
 
Click for Full Abstract

GENOA: Genetic Epidemiology Network of Arteriopathy
 Ethnic and Sex Differences in the Prevalence, Treatment, and Control of Dyslipidemia Among Hypertensive Adults in the GENOA Study

O’Meara JG, Kardia SLR, Armon JJ, Brown CA, Boerwinkle E, Turner ST.
Arch Intern Med.   2004;164:1313-1318.
  KEYWORDS: CHD , Hypertension


Click for Full Abstract

Cardiovascular medications and risk of cancer

Ocampo NV, Tafreshi J, Hauschild CL, Pai RG.
Am J Cardiol.   2011;108(7):1045-1051.
  KEYWORDS: CVD , HMG-CoA reductase inhibitor
 
Click for Full Abstract

ESTABLISH
 Early Statin Treatment in Patients With Acute Coronary Syndrome: Demonstration of the Beneficial Effect on Atherosclerotic Lesions by Serial Volumetric Intravascular Ultrasound Analysis During Half a Year After Coronary Event: The ESTABLISH Study

Okazaki S, Yokoyama T, Miyauchi K, et al.
Circulation.  2004;110:1061-1068.
  KEYWORDS: Angiography
 
Click for Full Abstract

Screening for Diabetes and Pre-Diabetes with Proposed A1C-Based Diagnostic Criteria

Olson DE, Rhee MK, Herrick K, Ziemer DC, Twombly JG, Phillips LS.
Diabetes Care.  2010;33(10):2184-2189.
  KEYWORDS: Diabetes
 
Click for Full Abstract

Ankle-Brachial Index as a Predictor of the Extent of Coronary Atherosclerosis and Cardiovascular Events in Patients with Coronary Artery Disease

Papamichael CM, Lekakis JP, Stamatelopoulos KS, et al.
Am J Cardiol.  2000;86:615-618.
  KEYWORDS: Atherosclerosis , CAD
 
Click for Full Abstract

Cardiovascular Disease Risk Factors in Chronic Kidney Disease: Overall Burden and Rates of Treatment and Control

Parikh NI, Hwang SJ, Larson MG, Meigs JB, Levy D, Fox CS.
Arch Intern Med.  2006;166:1884-1891.
  KEYWORDS: CVD , Diabetes , Framingham Heart Study , HDL-C , Hypertension , LDL-C
 
Click for Full Abstract

Adherence to Statin Therapy and LDL Cholesterol Goal Attainment by Patients With Diabetes and Dyslipidemia

Parris ES, Lawrence DB, Mohn LA, Long LB.
Diabetes Care.  2005;28:595-599.
  KEYWORDS: Diabetes , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

Systolic Blood Pressure, Diastolic Blood Pressure, and Pulse Pressure: An Evaluation of Their Joint Effect on Mortality

Pastor-Barriuso R, Banegas JR, Damián J, Appel LJ, Guallar E.
Ann Intern Med.   2003;139:731-739.
  KEYWORDS: CVD , Hypertension


Click for Full Abstract

Serum Triglycerides as a Risk Factor for Cardiovascular Diseases in the Asia-Pacific Region

Patel A, Barzi F, Jamrozik K, et al, for the Asia Pacific Cohort Studies Collaboration.
Circulation.  2004;110:2678-2686.
  KEYWORDS: CHD , CVD , Triglycerides
 
Click for Full Abstract

A Community-Based, Randomized Trial of Ezetimibe Added to Statin Therapy to Attain NCEP ATP III Goals for LDL Cholesterol in Hypercholesterolemic Patients: The Ezetimibe Add-On to Statin for Effectiveness (EASE) Trial

Pearson TA, Denke MA, McBride PE, Battisti WP, Brady WE, Palmisano J.
Mayo Clin Proc.  2005;80:587-595.
  KEYWORDS: ATP III , Combination therapy , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

Markers of Inflammation and Cardiovascular Disease Application to Clinical and Public Health Practice: A Statement for Healthcare Professionals From the Centers for Disease Control and Prevention and the American Heart Association

Pearson TA, Mensah GA, Alexander RW, et al.
Circulation.  2003;107:499-511.
  KEYWORDS: Atherosclerosis , CVD , Inflammation

Characteristics and Baseline Clinical Predictors of Future Fatal Versus Nonfatal Coronary Heart Disease Events in Older Adults: The Cardiovascular Health Study

Pearte CA, Furberg CD, O’Meara ES, et al.
Circulation.   2006;113:2177-2185.
  KEYWORDS: MI , Older adults
 
Click for Full Abstract

IDEAL: Incremental Decrease in End Points Through Aggressive Lipid Lowering Study
 High-Dose Atorvastatin vs Usual-Dose Simvastatin for Secondary Prevention After Myocardial Infarction. The IDEAL Study: A Randomized Controlled Trial

Pedersen TR, Faergeman O, Kastelein JJP, et al, for the Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) Study Group.
JAMA.  2005;294:2437-2445.
  KEYWORDS: HMG-CoA reductase inhibitor , LDL-C , MI

Hypertriglyceridemia

Pejic RN, Lee DT.
J Am Board Fam Med.  2006;19:310-316.
  KEYWORDS: CAD , HMG-CoA reductase inhibitor , Metabolic Syndrome , Omega-3 polyunsaturated fatty acids , Triglycerides

Exposure to Traffic and the Onset of Myocardial Infarction

Peters A, von Klot S, Heier M, et al, for the Cooperative Health Research in the Region of Augsburg Study Group.
N Engl J Med.   2004;351:1721-1730.
  KEYWORDS: MI

Dual Calcium Channel and Angiotensin Receptor Blockade is Superior to Amlodipine or Valsartan Alone for Optimal Hypertension Control

Philipp T, Glazer G, Wersing M, et al.

 

  KEYWORDS: Combination therapy , Hypertension

Aspirin, Statins, or Both Drugs for the Primary Prevention of Coronary Heart Disease Events in Men: A Cost-Utility Analysis

Pignone M, Earnshaw S, Tice JA, Pletcher MJ.
Ann Intern Med.  2006;144:326-336.
  KEYWORDS: Aspirin , CHD , Cost-effectiveness , HMG-CoA reductase inhibitor
 
Click for Full Abstract

Simvastatin Lowers C-Reactive Protein Within 14 Days: An Effect Independent of Low-Density Lipoprotein Cholesterol Reduction

Plenge JK, Hernandez TL, Weil KM, et al.
Circulation.  2002;106:1447-1452.
  KEYWORDS: CRP , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

Using the Coronary Artery Calcium Score to Predict Coronary Heart Disease Events

Pletcher MJ, Tice JA, Pignone M, Browner W.
Arch Intern Med.  2004;164:1285-1292.
  KEYWORDS: CHD
 
Click for Full Abstract

Carotid intima-media thickness in plaque-free site, carotid plaques and coronary heart disease risk prediction in older adults. The Three-City Study

Plichart M, Celermajer DS, Zureik M, Helmer C, Jouven X, Ritchie K, Tzourio C, Ducimetière P, Empana JP.
Atherosclerosis.   2011 Sep 28. [Epub ahead of print]
  KEYWORDS: Carotid atherosclerosis , CHD , CIMT , Risk assessment
 
Click for Full Abstract

Progression of Aortic Valve Calcification: Association With Coronary Atherosclerosis and Cardiovascular Risk Factors

Pohle K, Mäffert R, Ropers D, et al.
Circulation.  2001;104:1927-1932.
  KEYWORDS: Atherosclerosis , LDL-C
 
Click for Full Abstract

Segment-Specific Associations of Carotid Intima-Media Thickness with Cardiovascular Risk Factors: the Coronary Artery Risk Development in Young Adults (CARDIA) study

Polak JF, Person SD, Wei GS, et al.
Stroke.  2010;41(1):9-15.
  KEYWORDS: Carotid atherosclerosis , CIMT , Young adults
 
Click for Full Abstract

Coronary Artery Calcium Score and Risk Classification for Coronary Heart Disease Prediction

Polonsky TS, McClelland RL, Jorgensen NW, et al.
JAMA.  2010;303(16):1610-1616.
  KEYWORDS: Atherosclerosis , CHD

Statins and the Risk of Colorectal Cancer

Poynter JN, Gruber SB, Higgins PDR, et al.
N Engl J Med.  2005;352:2184-2192.
  KEYWORDS: HMG-CoA reductase inhibitor

An Association Between Atherosclerosis and Venous Thrombosis

Prandoni P, Bilora F, Marchiori A, et al.
N Engl J Med.  2003;348:1435-1441.
  KEYWORDS: Atherosclerosis , Inflammation , Thrombus

Antihypertensive Efficacy of the Direct Renin Inhibitor Aliskiren When Added to Hydrochlorothiazide Treatment in Patients With Extreme Obesity and Hypertension

Prescott MF, Boye SW, Breton SL, Keefe DL, Jordon J.

 

  KEYWORDS: BMI , Hypertension , Obesity/overweight

Cardiovascular Risk Factors in Childhood and Carotid Artery Intima-Media Thickness in Adulthood. The Cardiovascular Risk in Young Finns Study

Raitakari OT, Juonala M, Kähönen M, et al.
JAMA.  2003;290:2277-2283.
  KEYWORDS: Atherosclerosis , Carotid atherosclerosis , CIMT , CVD , Young adults

Effectiveness of a volunteer-delivered lifestyle modification program for reducing cardiovascular disease risk factors

Rankin P, Morton DP, Diehl H, Gobble J, Morey P, Chang E.
Am J Cardiol  2012;109(1):82-86.
  KEYWORDS: CVD , HDL-C , LDL-C , Risk assessment , Triglycerides

OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction

Rauch B, Schiele R, Schneider S, et al; for the OMEGA Study Group
Circulation.  2010;122(21):2152-2159.
  KEYWORDS: MI , Omega-3 polyunsaturated fatty acids
 
Click for Full Abstract

Incidence of New Stroke or New Myocardial Infarction or Death in Patients With Severe Carotid Arterial Disease Treated With and Without Statins

Ravipati G, Aronow WS, Ahn C, Channamsetty V, Sekhri V.
Am J Cardiol.   2006;98:1170-1171.
  KEYWORDS: HMG-CoA reductase inhibitor , MI
 
Click for Full Abstract

Screening Children to Identify Families at Increased Risk for Cardiovascular Disease

Reis EC, Kip KE, Marroquin OC, et al.
Pediatrics.  2006;118:e1789-e1797.
  KEYWORDS: BMI , CVD , Hypertension , Metabolic Syndrome , MI , Young adults
  
Click for Full Abstract

One-year Treatment With Rosuvastatin Reduces Intima-Media Thickness in 45 Hypercholesterolemic Subjects With Asymptomatic Carotid Artery Disease

Riccioni G, Vitulano N, Mancini B, Zanasi A, D'Orazio N.
Pharmacology.  2010;85(2):63-67.
  KEYWORDS: CIMT , HMG-CoA reductase inhibitor , Hypercholesterolemia
 
Click for Full Abstract

HERITAGE Family Study: Health, Risk Factors, Exercise Training, and Genetics
 Familial Aggregation of Blood Lipid Response to Exercise Training in the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study

Rice T, Després JP, Pérusse L, et al.
Circulation.  2002;105:1904-1908.
  KEYWORDS: Family history

C-Reactive Protein Levels and Outcomes after Statin Therapy

Ridker PM, Cannon CP, Morrow D, et al, for the Pravastatin or Atorvastatin Evaluation and Infection Therapy—Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators.
N Engl J Med.   2005;352:20-28.
  KEYWORDS: CAD , CRP , HMG-CoA reductase inhibitor , Inflammation , LDL-C , MI

A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease in Women

Ridker PM, Cook NR, Lee IM, et al.
N Engl J Med.  2005;352:1293-1304.
  KEYWORDS: Aspirin , CVD , MI , Women

JUPITER: Justification for the Use of statins in Primary prevention: an Intervention Trial Evaluating Rosuvastatin
 Baseline Characteristics of Participants in the JUPITER Trial, A Randomized Placebo-Controlled Primary Prevention Trial of Statin Therapy Among Individuals With Low Low-Density Lipoprotein Cholesterol and Elevated High-Sensitivity C-Reactive Protein

Ridker PM, Fonseca FA, Genest J, et al, for the JUPITER Trial Study Group.
Am J Cardiol.  2007;100(11):1659-1664.
  KEYWORDS: CRP , HMG-CoA reductase inhibitor , LDL-C

WHS: Women’s Health Study
 Comparison of C-reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events

Ridker PM, Rifai N, Rose L, Buring JE, Cook NR.
N Engl J Med.  2002;347:1557-1565.
  KEYWORDS: CRP , HRT , Inflammation , LDL-C , Women

VA-HIT: Veterans Affairs High-Density Lipoprotein Intervention Trial
 Insulin Resistance and Cardiovascular Events With Low HDL Cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT)

Robins SJ, Rubins HB, Faas FH, et al, on behalf of the VA-HIT Study Group.
Diabetes Care.  2003;26:1513-1517.
  KEYWORDS: CHD , Diabetes , Fibric acid , HDL-C , Insulin resistance
 
Click for Full Abstract

Acute Effects of Statin Therapy on Coronary Atherosclerosis Following an Acute Coronary Syndrome

Rodés-Cabau J, Tardif JC, Cossette M, et al.
Am J Cardiol.   2009;104(6):750-757.
  KEYWORDS: ACS , Atherosclerosis , HMG-CoA reductase inhibitor

VA-HIT: Veterans Affairs High-Density Lipoprotein Intervention Trial
 Diabetes, Plasma Insulin, and Cardiovascular Disease: Subgroup Analysis From the Department of Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT)

Rubins HB, Robins SJ, Collins D, et al, for the VA-HIT Study Group.
Arch Intern Med.  2002;162:2597-2604.
  KEYWORDS: CVD , Diabetes , HDL-C , Insulin resistance
 
Click for Full Abstract

Lifestyle Intervention for Prevention of Type 2 Diabetes in Primary Health Care: One-Year Follow-up of the Finnish National Diabetes Prevention Program (FIN-D2D)

Saaristo T, Moilanen L, Korpi-Hyövälti E, Vanhala M, et al.
Diabetes Care.  2010;33(10):2146-2151.
  KEYWORDS: Diabetes
 
Click for Full Abstract

Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly With Type 2 Diabetes Mellitus

Sakurai T, Iimuro S, Araki A, et al.
Gerontology.  2010;56(2):141-149.
  KEYWORDS: CVD , Diabetes , Insulin resistance , Metabolic Syndrome , Obesity/overweight , Older adults
 
Click for Full Abstract

Bariatric surgery versus intensive medical therapy in obese patients with diabetes

Schauer PR, Kashyap SR, Wolski K, et al.
N Engl J Med  March 26, 2012. Epub ahead of print.
  KEYWORDS: BMI , Diabetes , Obesity/overweight

Vascular Structural and Functional Changes in Type 2 Diabetes Mellitus: Evidence for the Roles of Abnormal Myogenic Responsiveness and Dyslipidemia

Schofield I, Malik R, Izzard A, Austin C, Heagerty A.
Circulation.  2002;106:3037-3043.
  KEYWORDS: Diabetes , Endothelium


Click for Full Abstract

MIRACL: Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering
 Effects of Atorvastatin on Early Recurrent Ischemic Events in Acute Coronary Syndromes; The MIRACL Study: A Randomized Controlled Trial

Schwartz GG, Olsson A, Ezekowitz MD, et al, for the MIRACL Study Investigators.
JAMA.  2001;285:1711-1718.
  KEYWORDS: HMG-CoA reductase inhibitor , MI

Metabolic Syndrome Amplifies the Age-Associated Increases in Vascular Thickness and Stiffness

Scuteri A, Najjar SS, Muller DC, et al.
J Am Coll Cardiol.   2004;43:1388-1395.
  KEYWORDS: Atherosclerosis , CIMT , Metabolic Syndrome
 
Click for Full Abstract

ASCOT-LLA: Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm
 Prevention of Coronary and Stroke Events With Atorvastatin in Hypertensive Patients Who Have Average or Lower-Than-Average Cholesterol Concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): A Multicentre Randomised Controlled Trial

Sever PS, Dahlöf B, Poulter NR, et al, for the ASCOT Investigators.
Lancet.  2003;361:1149-1158.
  KEYWORDS: CHD , HMG-CoA reductase inhibitor , Hypertension

Reduction in Cardiovascular Events With Atorvastatin in 2,532 Patients With Type 2 Diabetes

Sever PS, Poulter NR, Dahlöf B, et al, for the ASCOT Investigators.
Diabetes Care.  2005;28:1151-1157.
  KEYWORDS: CHD , Diabetes , HMG-CoA reductase inhibitor , Hypertension

Multivariate Assessment of Lipid Parameters as Predictors of Coronary Heart Disease Among Postmenopausal Women: Potential Implications for Clinical Guidelines

Shai I, Rimm EB, Hankinson SE, et al.
Circulation.  2004;110:2824-2830.
  KEYWORDS: CHD , CRP , HDL-C , LDL-C , Obesity/overweight , Women
 
Click for Full Abstract

Effect of Lowering LDL Cholesterol Substantially Below Currently Recommended Levels in Patients With Coronary Heart Disease and Diabetes: The Treating to New Targets (TNT) Study

Shepherd J, Barter P, Carmena R, et al, for the Treating to New Targets Investigators.
Diabetes Care.  2006;29:1220-1226.
  KEYWORDS: CHD , Diabetes , HMG-CoA reductase inhibitor , LDL-C
 
Click for Full Abstract

PROSPER: PROspective Study of Pravastatin in the Elderly at Risk
 Pravastatin in Elderly Individuals at Risk of Vascular Disease (PROSPER): A Randomised Controlled Trial

Shepherd J, Blauw GJ, Murphy MB, et al, on behalf of the PROSPER study group.
Lancet.  2002;360:1623-1630.
  KEYWORDS: CHD , CVD , HMG-CoA reductase inhibitor , Older adults
 
Click for Full Abstract

Higher Heart Rate May Predispose to Obesity and Diabetes Mellitus: 20-Year Prospective Study in a General Population

Shigetoh Y, Adachi H, Yamagishi S, et al.
American Journal of Hypertension.  2009;22(2):151-155.
  KEYWORDS: Diabetes , Hypertension

Postmenopausal Hormone Therapy and Risk of Stroke: The Heart and Estrogen-progestin Replacement Study (HERS)

Simon JA, Hsia J, Cauley JA, et al.
Circulation.  2001;103:638-642.
  KEYWORDS: HRT , Women
 
Click for Full Abstract

Phenotypic Predictors of Response to Simvastatin Therapy Among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study

Simon JA, Lin F, Hulley SB, et al.
Am J Cardiol.  2006;97:843-850.
  KEYWORDS: HDL-C , HMG-CoA reductase inhibitor , LDL-C , Triglycerides
 
Click for Full Abstract

Influence of Insulin Resistance and Body Mass Index at Age 13 on Systolic Blood Pressure, Triglycerides, and High-Density Lipoprotein Cholesterol at Age 19

Sinaiko AR, Steinberger J, Moran A, Hong CP, Prineas RJ, Jacobs DR Jr.
Hypertension.  2006;48:1-7.
  KEYWORDS: BMI , HDL-C , Hypertension , Metabolic Syndrome , MI , Triglycerides , Young adults

Lipid Control in the Management of Type 2 Diabetes Mellitus: A Clinical Practice Guideline from the American College of Physicians

Snow V, Aronson MD, Hornbake ER, Mottur-Pilson, C, Weiss KB, for the Clinical Efficacy Assessment Subcommittee of the American College of Physicians.
Ann Intern Med.   2004;140:644-649.
  KEYWORDS: Diabetes , HMG-CoA reductase inhibitor
 
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Association Between Carotid Intima-Media Thickness and Pericardial Fat in the Multi-Ethnic Study of Atherosclerosis (MESA)

Soliman EZ, Ding J, Hsu FC, Carr JJ, Polak JF, Goff DC Jr.
J Stroke Cerebrovasc Dis.   2010;19(1):58-65.
  KEYWORDS: Atherosclerosis , CIMT
 
Click for Full Abstract

PEACE: Prevention of Events with ACE inhibition trial
 Influence of Albuminuria on Cardiovascular Risk in Patients With Stable Coronary Artery Disease

Solomon SD, Lin J, Solomon CG, et al, for the Prevention of Events With ACE Inhibition (PEACE) Investigators.
Circulation.  2007;116(23):2687-2693.
  KEYWORDS: CAD , CVD , Diabetes
 
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Association of Fibrinogen with Cardiovascular Risk Factors and Cardiovascular Disease in the Framingham Offspring Population

Stec JJ, Silbershatz H, Tofler GH, et al.
Circulation.  2000;102:1634-1638.
  KEYWORDS: Fibric acid , Framingham Heart Study

GRACE: Global Registry of Acute Coronary Events
 Baseline Characteristics, Management Practices, and In-Hospital Outcomes of Patients Hospitalized With Acute Coronary Syndromes in the Global Registry of Acute Coronary Events (GRACE)

Steg PG, Goldberg RJ, Gore JM, et al, for the GRACE Investigators.
Am J Cardiol.  2002;90:358-363.
  KEYWORDS: MI
 
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Swedish Registry Study: Swedish Register of Cardiac Intensive Care
 Early Statin Treatment Following Acute Myocardial Infarction and 1-Year Survival

Stenestrand U, Wallentin L, for the Swedish Register of Cardiac Intensive Care (RIKS-HIA).
JAMA.  2001;285:430-436.
  KEYWORDS: HMG-CoA reductase inhibitor , MI

The Effects of Low-Carbohydrate versus Conventional Weight Loss Diets in Severely Obese Adults: One-Year Follow-up of a Randomized Trial

Stern L, Iqbal N, Seshadri P, et al.
Ann Intern Med.  2004;140:778-785.
  KEYWORDS: Diabetes , Diet , HDL-C , LDL-C , Obesity/overweight

Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion

Stolarz-Skrzypek K, Kuznetsova T, Thijs L, et al for the European Project on Genes in Hypertension (EPOGH) Investigators.
JAMA.   2011;305(17):1777-1785.
  KEYWORDS: Hypertension

Low Cholesterol, Mortality, and Quality of Life in Old Age During a 39-Year Follow-Up

Strandberg TE, Strandberg A, Rantanen K, Salomaa VV, Pitkälä K, Miettinen TA.
J Am Coll Cardiol.   2004;44:1002-1008.
  KEYWORDS: Older adults
 
Click for Full Abstract

Under-Recognition of the Metabolic Syndrome and Actual Cardiovascular Risk in Women

Strimike C, Latrella M, Faillace R.

 

  KEYWORDS: ATP III , Metabolic Syndrome , Women

Intensive lowering of LCL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group.
Lancet.   2010;376(9753):1658-1669.
  KEYWORDS: HMG-CoA reductase inhibitor

Tolerability of Statin-Fibrate and Statin-Niacin Combination Therapy in Dyslipidemic Patients at High Risk for Cardiovascular Events

Taher TH, Dzavik V, Reteff EM, Pearson GJ, Woloschuk BL, Francis GA.
Am J Cardiol.  2002;89:390-394.
  KEYWORDS: Combination therapy , Fibric acid , HMG-CoA reductase inhibitor , Nicotinic acid
 
Click for Full Abstract

Relationship Between Common Carotid Intima-Media Thickness and Thoracic Aortic Calcification: the Multi-Ethnic Study of Atherosclerosis

Takasu J, Budoff MJ, Katz R, et al.
Atherosclerosis.   2010;209(1):142-146.
  KEYWORDS: Atherosclerosis , Carotid atherosclerosis , CIMT
 
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Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: A Double-Blind, Placebo-Controlled Study of Extended-Release Niacin on Atherosclerosis Progression in Secondary Prevention Patients Treated With Statins

Taylor AJ, Sullenberger LE, Lee HJ, Lee JK, Grace KA.
Circulation.  2004;110:3512-3517.
  KEYWORDS: Atherosclerosis , Carotid atherosclerosis , CHD , Combination therapy , HDL-C , HMG-CoA reductase inhibitor
 
Click for Full Abstract

Extended-release niacin or ezetimibe and carotid intima-media thickness

Taylor AJ, Villines TC, Stanek EJ, et al.
N Engl J Med.  2009;361(22):2113-2122.
  KEYWORDS: CIMT , Combination therapy , Ezetimibe , HMG-CoA reductase inhibitor
This prospective, randomized, parallel-group, open-label study with blinded endpoint evaluation assessed the effects of niacin extended release (ER) or ezetimibe on carotid intima-media thickness (CIMT) when both were combined with statin therapy.a
 
Subjects (N=208) had a mean age of 65 years and 80% were male. They had either known atherosclerotic coronary or vascular disease or coronary heart disease equivalent, 10-year Framingham risk score ≥20%, or coronary artery calcium score >200 for women or >400 for men; were receiving statin therapy for mean of 6±5 years (95% were receiving atorvastatin or simvastatin; mean dose was 42±25 mg); and had LDL-C ≤100 mg/dL and HDL-C ≤50 mg/dL (men) or ≤55 mg/dL (women).
 
Subjects received niacin ER up to 2,000 mg qd (increased from an initial dose of 500 mg at bedtime by 500 mg every other week to maximum tolerated dose [up to 2,000 mg])+ statin (n=97) or ezetimibe 10 mg qd + statin (n=111). The study’s primary endpoint was between-group difference in change in mean CIMT after 14 months.a
 
At 14 months, niacin therapy had a greater effect on change in mean and maximal CIMT vs ezetimibe. There was a significant between-group difference of P=0.003 for the repeated-measures analysis.
 
A significant reduction in mean CIMT was observed in the niacin group between 8 and 14 months (P=0.02).  No significant net changes in CIMT were seen with ezetimibe. However, there was a significant inverse relationship between changes in LDL-C level and CIMT among ezetimibe-treated subjects (R=−0.31, P<0.001), such that a paradoxical increase in CIMT was seen among those with greater reductions in LDL-C. This inverse relationship was not observed among niacin-treated subjects (R=−0.01, P=0.92). There was a higher incidence of major adverse cardiovascular events among subjects in the ezetimibe group vs the niacin group (5% vs 1%; P=0.04 by the chi-square test).
 
aThe agents used in this study are not FDA approved to treat the endpoint discussed (CIMT)

Click for Full Abstract

Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes

The ACCORD Study Group and ACCORD Eye Study Group.
N Engl J Med.  2010;363(3):233-244.
  KEYWORDS: Diabetes , Fibric acid , HMG-CoA reductase inhibitor , Hypertension

ACCORD: Action to Control Cardiovascular Risk in Diabetes
 Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

The ACCORD Study Group.
N Engl J Med.  2010;Epub ahead of print.
  KEYWORDS: Combination therapy , CVD , Diabetes , Fibric acid , HMG-CoA reductase inhibitor

ACCORD: Action to Control Cardiovascular Risk in Diabetes
 Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus

The ACCORD Study Group.
N Engl J Med.  2010;Epub ahead of print.
  KEYWORDS: CVD , Diabetes , Hypertension

ACCORD: Action to Control Cardiovascular Risk in Diabetes
 The Action to Control Cardiovascular Risk in Diabetes Study Group

The Action to Control Cardiovascular Risk in Diabetes Study Group.
N Engl J Med.  2008;358(24):2545-2559.
  KEYWORDS: CAD , Diabetes

ADVANCE: Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation
 Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

The ADVANCE Collaborative Group.
N Engl J Med.  2008;358(24):2560-2572.
  KEYWORDS: Diabetes

C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis

The Emerging Risk Factors Collaboration
Lancet.  2009; Epub ahead of print. doi:10.1016/S0140-6736(09)61717-7.
  KEYWORDS: CRP , CVD

C-reactive Protein Concentration and Risk of Coronary Heart Disease, Stroke, and Mortality: an Individual Participant Meta-Analysis

The Emerging Risk Factors Collaboration.
Lancet.  2010;Epub ahead of print.
  KEYWORDS: CRP

Sex-Specific Trends in Midlife Coronary Heart Disease Risk and Prevalence

Towfighi A, Zheng L, Ovbiagele B.
Arch Intern Med.   2009;169(19):1762-1766.
  KEYWORDS: CHD , CVD

WASID: Warfarin-Aspirin Symptomatic Intracranial Disease trial
 Relationship Between Blood Pressure and Stroke Recurrence in Patients With Intracranial Arterial Stenosis

Turan TN, Cotsonis G, Lynn MJ, Chaturvedi S, Chimowitz M, for the Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) Trial Investigators.
Circulation.  2007;115(23):2969-2975.
  KEYWORDS: Aspirin , Hypertension

High Prevalence of Coronary Atherosclerosis in Asymptomatic Teenagers and Young Adults: Evidence From Intravascular Ultrasound

Tuzcu EM, Kapadia SR, Tutar E, et al.
Circulation.  2001;103:2705-2710.
  KEYWORDS: Atherosclerosis , Young adults


Click for Full Abstract

Using Nontraditional Risk Factors in Coronary Heart Disease Risk Assessment: U.S. Preventive Services Task Force Recommendation Statement

U.S. Preventive Services Task Force.
Ann Intern Med.  2009;151(7):474-482.
  KEYWORDS: CHD
 
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ORION: Outcome of Rosuvastatin treatment on carotid artery atheroma: a magnetic resonance Imaging ObservatioN
 Effect of Rosuvastatin Therapy on Carotid Plaque Morphology and Composition in Moderately Hypercholesterolemic Patients: a High-Resolution Magnetic Resonance Imaging Trial

Underhill HR, Yuan C, Zhao X-Q, et al.
Am Heart J.  2008;155(3):584.e1-e8
  KEYWORDS: Carotid atherosclerosis , HMG-CoA reductase inhibitor , Hypercholesterolemia , LDL-C , Plaque

Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes

Unick JL, Beavers D, Jakicic JM, et al; for the Look AHEAD Research Group.
Diabetes Care.  2011;34(10):2152 2157.
  KEYWORDS: BMI , Diabetes , Diet , Exercise , Obesity/overweight

Association of Serum Adiponectin With Risk for Cardiovascular Events in Patients With Peripheral Arterial Disease

Urbonaviciene G, Frystyk J, Flyvbjerg A, Henneberg EW, Lindholt JS.
Atherosclerosis.  2010 Jan 4. [Epub ahead of print].
  KEYWORDS: PAD
 
Click for Full Abstract

Comparative effectiveness and cost-effectiveness of computed tomography screening for coronary artery calcium in asymptomatic individuals

van Kempen BJ, Spronk S, Koller MT, Elias-Smale SE, Fleischmann KE, Ikram MA, Krestin GP, Hofman A, Witteman JC, Hunink MG.
J Am Coll Cardiol.   2011;58(16):1690-1701.
  KEYWORDS: Cost-effectiveness , Risk assessment
 
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Clinical use of liraglutide in type 2 diabetes and its effects on cardiovascular risk factors

Varanasi A, Patel P, Makdissi A, Dhindsa S, Chaudhuri A, Dandona P.
Endocr Pract.   2011 Aug 19:1-13. Epub ahead of print.
  KEYWORDS: CVD , Diabetes

ARBITER 6-HALTS: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6–HDL and LDL Treatment Strategies in Atherosclerosis
 The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6–HDL and LDL Treatment Strategies in Atherosclerosis). Final Results and Impact of Medication Adherence, Dose, and Treatment Duration

Villines TC, Stanek EJ, Devine PJ, et al.
J Am Coll Cardiol.   2010;55(24):doi:10.1016/j.jacc.2010.03.017
  KEYWORDS: Atherosclerosis , Carotid atherosclerosis , CIMT , Combination therapy , Ezetimibe , HMG-CoA reductase inhibitor , Nicotinic acid

HERS: Heart and Estrogen/progestin Replacement Study
 Risk Factors and Secondary Prevention in Women with Heart Disease: The Heart and Estrogen/progestin Replacement Study

Vittinghoff E, Shlipak MG, Varosy PD, et al, for the Heart and Estrogen/progestin Replacement Study Research Group
Ann Intern Med.  2003;138:81-89.
  KEYWORDS: CHD , HRT , MI , Women

 
Click for Full Abstract

Alcohol Consumption and Coronary Calcification in a General Population

Vliegenthart R, Oei HHS, van den Elzen APM, et al.
Arch Intern Med.  2004;164:2355-2360.
  KEYWORDS: Alcohol consumption , Atherosclerosis


Click for Full Abstract

Relation Between Progression and Regression of Atherosclerotic Left Main Coronary Artery Disease and Serum Cholesterol Levels as Assessed With Serial Long-Term (≥12 Months) Follow-Up Intravascular Ultrasound

von Birgelen C, Hartmann M, Mintz GS, Baumgart D, Schmermund A, Erbel R.
Circulation.  2003;108: 2757-2762.
  KEYWORDS: Atherosclerosis , CAD , HDL-C , LDL-C

Click for Full Abstract

Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals.

Voulgari C, Tentolouris N, Dilaveris P, Tousoulis D, Katsilambros N, Stefanadis C.
J Am Coll Cardiol.   2011;58(13):1343-1350.
  KEYWORDS: Heart failure , Metabolic Syndrome , Obesity/overweight
 
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Statin Therapy, Inflammation and Recurrent Coronary Events in Patients Following Coronary Stent Implantation

Walter DH, Fichtlscherer S, Britten MB, et al.
J Am Coll Cardiol.  2001;38:2006-2012.
  KEYWORDS: CRP , HMG-CoA reductase inhibitor , Inflammation , Stents
 
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Exertional Leg Pain in Patients With and Without Peripheral Arterial Disease

Wang JC, Criqui MH, Denenberg JO, McDermott MM, Golomb BA, Fronek A.
Circulation.  2005;112:3501-3508.
  KEYWORDS: PAD , Revascularization
 
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Efficacy of Folic Acid Supplementation in Stroke Prevention: A Meta-Analysis

Wang X, Qin X, Demirtas H, et al.
Lancet.  2007;369(9576):1876-1882.
  KEYWORDS: CAD , Folic acid

Association Between Cardiovascular Outcomes and Antihypertensive Drug Treatment in Older Women

Wassertheil-Smoller S, Psaty B, Greenland P, et al.
JAMA.  2004;292:2849-2859.
  KEYWORDS: Combination therapy , CVD , Hypertension , Older adults , Women

MIRACL: Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering
 Effects of Atorvastatin on Stroke in Patients With Unstable Angina or Non–Q-Wave Myocardial Infarction: A Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Substudy

Waters DD, Schwartz GG, Olsson AG, et al, for the MIRACL Study Investigators.
Circulation.  2002;106:1690-1695.
  KEYWORDS: HMG-CoA reductase inhibitor , MI
 
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Blood Pressure and the Risk of Developing Diabetes in African Americans and Whites: ARIC, CARDIA, and the Framingham Heart Study

Wei GS, Coady SA, Goff DC Jr, Brancati FL, Levy D, Selvin E, Vasan RS, Fox CS
Diabetes Care  2011 Feb 23. [Epub ahead of print]
  KEYWORDS: Diabetes , Framingham Heart Study , Risk assessment
 
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Leptin Predicts Diabetes but Not Cardiovascular Disease: Results from a Large Prospective Study in an
Elderly Population

Welsh P, Murray HM, Buckley BM, et al.
Diabetes Care.  2009;32(2):308-310.
  KEYWORDS: BMI , CVD , Diabetes , HMG-CoA reductase inhibitor , Older adults

Clinical and Angiographic Predictors of Restenosis After Stent Deployment in Diabetic Patients

West NEJ, Ruygrok PN, Disco CMC, et al.
Circulation.   2004;109:867-873.
  KEYWORDS: Angiography , BMI , Diabetes , PCI


Click for Full Abstract

High-Density vs Low-Density Lipoprotein Cholesterol as the Risk Factor for Coronary Artery Disease and Stroke in Old Age

Weverling-Rijnsburger AWE, Jonkers IJAM, van Exel E, Gussekloo J, Westendorp RGJ.
Arch Intern Med.  2003;163:1549-1554.
  KEYWORDS: CAD , HDL-C , LDL-C , Older adults
 
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A Randomized Trial of a Strategy for Increasing High-Density Lipoprotein Cholesterol Levels: Effects on Progression of Coronary Heart Disease and Clinical Events

Whitney EJ, Krasuski RA, Personius BE, et al.
Ann Intern Med.  2005;142:95-104.
  KEYWORDS: CHD , Combination therapy , HDL-C , LDL-C


Click for Full Abstract

Effects of Pioglitazone on Major Adverse Cardiovascular Events in High-Risk Patients with Type 2 Diabetes: Results from Prospective Pioglitazone Clinical Trial In Macro Vascular Events (Proactive 10)

Wilcox R, Kupfer S, Erdmann E, et al, for the PROactive Study Investigators.
Am Heart J.  2008;155(4):712-717.
  KEYWORDS: CAD , CHD , CVD , Diabetes , MI

Usefulness of Cardiovascular Family History Data for Population-Based Preventive Medicine and Medical Research (The Health Family Tree Study and the NHLBI Family Heart Study)

Williams RR, Hunt SC, Heiss G, et al.
Am J Cardiol.  2001;87:129-135.
  KEYWORDS: CHD , Family history

Prevalence, Treatment, and Control of Combined Hypertension and Hypercholesterolemia in the United States

Wong ND, Lopez V, Tang S, Williams R.
Am J Cardiol.   2006;98:204-208.
  KEYWORDS: CVD , HDL-C , Hypertension , LDL-C

 
Click for Full Abstract

First-line Drugs for Hypertension

Wright JM, Musini VM.
Cochrane Database Syst Rev.  2009;(3):CD001841.
  KEYWORDS: CVD , Hypertension

Association of Low Glomerular Filtration Rate and Albuminuria With Peripheral Arterial Disease: the National Health and Nutrition Examination Survey, 1999-2004

Wu CK, Yang CY, Tsai CT,
Atherosclerosis.   2010;209(1):230-234.
  KEYWORDS: Atherosclerosis , PAD
 
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Education, 15-Year Risk Factor Progression, and Coronary Artery Calcium in Young Adulthood and Early Middle Age: The Coronary Artery Risk Development in Young Adults Study

Yan LL, Liu K, Daviglus ML, et al.
JAMA.   2006;295:1793-1800.
  KEYWORDS: CAD , CVD , Young adults

A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet to Treat Obesity and Hyperlipidemia

Yancy WS Jr, Olsen MK, Guyton JR, Bakst RP, Westman EC.
Ann Intern Med.   2004;140:769-777.
  KEYWORDS: BMI , Diet , HDL-C , Hypertension , LDL-C , MI , Obesity/overweight

C-Reactive Protein Is Associated With Arterial Stiffness in Apparently Healthy Individuals

Yasmin, McEniery CM, Wallace S, Mackenzie IS, Cockcroft JR, Wilkinson IB.
Arterioscler Thromb Vasc Biol.  2004;24:969-974.
  KEYWORDS: Atherosclerosis , CRP , Inflammation
 
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Obesity and the Risk of Myocardial Infarction in 27,000 Participants From 52 Countries: A Case-Control Study

Yusuf S, Hawken S, Ôunpuu S, et al, for the INTERHEART Study Investigators.
Lancet.  2005;366:1640-1649.
  KEYWORDS: BMI , MI
 
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Impact of obesity on cardiovascular disease

Zalesin KC, Franklin BA, Miller WM, Peterson ED, McCullough PA.
Med Clin North Am.   2011;95(5):919-937.
  KEYWORDS: CVD , Obesity/overweight
 
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