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Understanding the Terms

HDL-C: High-density lipoprotein (the "good") cholesterol protects against the development of coronary heart disease. It transports cholesterol from the body cells to the liver, where it is excreted in bile. Decreased levels are linked to coronary heart disease risk. Optimal HDL-C level: more than 35 mg/dL.*

LDL-C: Low-density lipoprotein (the "bad") cholesterol, formed in the circulation, that transports cholesterol from the liver to other body tissues. Elevated levels are linked to coronary heart disease risk. Optimal LDL-C level: less than 130 mg/dL.*

Lipoprotein: Protein-covered fat particles that help cholesterol and triglycerides move throughout the body.

Triglycerides: A type of fat, made by the liver or ingested through the diet, that circulates in the blood. Elevated levels are associated with coronary heart disease risk. Optimal triglyceride level: less than 200 mg/dL.

*
Optimal Total Cholesterol level: less than 200 mg/dL.



Supported by an unrestricted educational grant from Pfizer Inc.



 
What Your Doctor Means By "Acute Coronary Syndromes"

It seems that almost every time you turn on the news nowadays you are bombarded with alarming statistics of the "health concern of the day." In that jungle of data and medical language, however, there is one constant: More people in the United States die of heart disease than of any other medical condition.
   The term "acute coronary syndromes" describes the class of major heart-disease–related events that includes heart attacks, or acute myocardial infarction (acute MI), and unstable angina (see definitions below). Preventing ACS has emerged as an important health priority in today's worldwide medical community. Cardiologists, researchers, and other specialists are investigating how to reduce the risks for the first ACS in healthy patients and for a recurring ACS in patients who already survived one.
   Traditionally, treatments for ACS include aspirin, prescription anticlotting medicine, or, in some cases, surgery (an example being revascularization). In their studies of new ways to treat the problem, medical researchers are investigating "statins"—or prescription drugs that improve cholesterol and triglyceride levels. Research suggests that this treatment may protect patients both immediately after an ACS (when the risk is highest for a subsequent event and death) and over the long term. More studies are ongoing in this field.
   Your physician can provide you with more information about this and other types of treatment for coronary events. But remember: No matter which treatment your doctor recommends, you need to take an active role and become a true partner in your healthcare plan. Without your commitment to lifestyle changes—eating a proper diet, quitting smoking, and getting enough exercise—any treatment effort will be futile. So, together you and your doctor can make a big impact on the war against heart disease, thus making "today's health concern" much less disturbing.

Acute coronary syndromes: Adverse coronary events, such as unstable angina and acute myocardial infarction, in which the primary culprit is atherosclerosis.

Acute myocardial infarction: Also called acute MI or heart attack. An MI occurs when blood flow is decreased or cut off to an area of the heart, and that section of the heart subsequently dies. Heart rhythm can be disturbed during a heart attack, sometimes causing sudden death.

Angioplasty:
During this procedure, a small balloon at the end of a catheter is inserted and inflated in narrowed or blocked blood vessels of the heart muscle, restoring blood flow.

Atherosclerosis:
Also known as hardening of the arteries, this disease occurs when plaque, or fatty substance, builds up in the vessel wall, which restricts blood flow.

Events:
Episodes or occurrences of a particular nature, such as cardiovascular.

Heart bypass:
This surgery relieves blockages in the heart muscle's blood vessels. Vein grafts are connected above and below the blockage, which allows blood to flow to the heart muscle.

Plaque:
Atherosclerotic plaque consists of fatty deposits on the inner lining of the arteries, blocking blood flow to the heart muscle.

Revascularization:
A surgical procedure that restores an adequate supply of blood (in this case, to the heart) by means of a blood vessel graft.

Unstable angina:
Commonly experienced as deep or poorly localized chest or arm pain that occurs when the heart isn't getting enough oxygen. When angina occurs severely or with little stress or exertion, it is referred to as "unstable" and may signify an impending heart attack.